Cargando…

High Glucose and Carbonyl Stress Impair HIF-1-Regulated Responses and the Control of Mycobacterium tuberculosis in Macrophages

Diabetes mellitus (DM) increases the risk of developing tuberculosis (TB), but the mechanisms behind diabetes-TB comorbidity are still undefined. Here, we studied the role of hypoxia-inducible factor-1 (HIF-1), a main regulator of metabolic and inflammatory responses, in the outcome of Mycobacterium...

Descripción completa

Detalles Bibliográficos
Autores principales:	Terán, Graciela, Li, Hanxiong, Catrina, Sergiu-Bogdan, Liu, Ruining, Brighenti, Susanna, Zheng, Xiaowei, Grünler, Jakob, Nylén, Susanne, Carow, Berit, Rottenberg, Martin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600926/ https://www.ncbi.nlm.nih.gov/pubmed/36121152 http://dx.doi.org/10.1128/mbio.01086-22

Ejemplares similares

HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection
por: Liu, Ruining, et al.
Publicado: (2022)

Publisher Correction: HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection
por: Liu, Ruining, et al.
Publicado: (2022)

Mycobacteria-Specific T Cells Are Generated in the Lung During Mucosal BCG Immunization or Infection With Mycobacterium tuberculosis
por: Basile, Juan I., et al.
Publicado: (2020)

DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance
por: Zhang, Juan, et al.
Publicado: (2021)

SOCS3, a Major Regulator of Infection and Inflammation
por: Carow, Berit, et al.
Publicado: (2014)

TRIM21 controls Toll‐like receptor 2 responses in bone‐marrow‐derived macrophages
por: Sjöstrand, Maria, et al.
Publicado: (2019)

STAT3 expression by myeloid cells is detrimental for the T- cell-mediated control of infection with Mycobacterium tuberculosis
por: Gao, Yu, et al.
Publicado: (2018)

Spatial Resolution of Mycobacterium tuberculosis Bacteria and Their Surrounding Immune Environments Based on Selected Key Transcripts in Mouse Lungs
por: Magoulopoulou, Anastasia, et al.
Publicado: (2022)

Critical and Independent Role for SOCS3 in Either Myeloid or T Cells in Resistance to Mycobacterium tuberculosis
por: Carow, Berit, et al.
Publicado: (2013)

Hypoxia and hypoxia-inducible factors in diabetes and its complications
por: Catrina, Sergiu-Bogdan, et al.
Publicado: (2021)

Protective Effect of the HIF-1A Pro582Ser Polymorphism on Severe Diabetic Retinopathy
por: Ekberg, Neda Rajamand, et al.
Publicado: (2019)

Corrigendum to “Protective Effect of the HIF-1A Pro582Ser Polymorphism on Severe Diabetic Retinopathy”
por: Ekberg, Neda Rajamand, et al.
Publicado: (2021)

SOCS2 expression in bone marrow derived dendritic cells is a positive regulator of T cell activation
por: Hu, Jin, et al.
Publicado: (2012)

Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma
por: Carow, Berit, et al.
Publicado: (2019)

Impact of the Hypoxia-Inducible Factor-1 α (HIF1A) Pro582Ser Polymorphism on Diabetes Nephropathy
por: Gu, Harvest F., et al.
Publicado: (2013)

Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate
por: Botusan, Ileana Ruxandra, et al.
Publicado: (2018)

SOCS3 Expression by Thymic Stromal Cells Is Required for Normal T Cell Development
por: Gao, Yu, et al.
Publicado: (2021)

LPS Regulates SOCS2 Transcription in a Type I Interferon Dependent Autocrine-Paracrine Loop
por: Hu, Jin, et al.
Publicado: (2012)

HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism
por: Narayanan, Sampath, et al.
Publicado: (2020)

Expression of M. tuberculosis-induced suppressor of cytokine signaling (SOCS) 1, SOCS3, FoxP3 and secretion of IL-6 associates with differing clinical severity of tuberculosis
por: Masood, Kiran I, et al.
Publicado: (2013)

Macrophage Migration Inhibitory Factor (MIF) Is Essential for Type 2 Effector Cell Immunity to an Intestinal Helminth Parasite
por: Filbey, Kara J., et al.
Publicado: (2019)

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
por: Braian, Clara, et al.
Publicado: (2015)

Repressed hypoxia inducible factor‐1 in diabetes aggravates pulmonary aspergillus fumigatus infection through modulation of inflammatory responses
por: Ye, Yao, et al.
Publicado: (2021)

Polarization of Human Monocyte-Derived Cells With Vitamin D Promotes Control of Mycobacterium tuberculosis Infection
por: Rao Muvva, Jagadeeswara, et al.
Publicado: (2020)

Insulin-like growth factor-I receptor activity is essential for Kaposi's sarcoma growth and survival
por: Catrina, S-B, et al.
Publicado: (2005)

A CFSE-based Assay to Study the Migration of Murine Skin Dendritic Cells into Draining Lymph Nodes During Infection with Mycobacterium bovis Bacille Calmette-Guérin
por: Bollampalli, Vishnu Priya, et al.
Publicado: (2016)

Atrophy of skin-draining lymph nodes predisposes for impaired immune responses to secondary infection in mice with chronic intestinal nematode infection
por: Feng, Xiaogang, et al.
Publicado: (2018)

Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue
por: Parasa, Venkata Ramanarao, et al.
Publicado: (2014)

Nature of Amide Carbonyl−Carbonyl Interactions in Proteins
por: Choudhary, Amit, et al.
Publicado: (2009)

Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes
por: Zheng, Xiaowei, et al.
Publicado: (2022)

Relative orientation of the carbonyl groups determines the nature of orbital interactions in carbonyl–carbonyl short contacts
por: Sahariah, Biswajit, et al.
Publicado: (2018)

Carbonyl Cyanide 3-Chlorophenylhydrazone (CCCP) Exhibits Direct Antibacterial Activity Against Mycobacterium abscessus
por: Chen, Suting, et al.
Publicado: (2021)

Reciprocal carbonyl–carbonyl interactions in small molecules and proteins
por: Rahim, Abdur, et al.
Publicado: (2017)

Lipid droplet formation in Mycobacterium tuberculosis infected macrophages requires IFN-γ/HIF-1α signaling and supports host defense
por: Knight, Matthew, et al.
Publicado: (2018)

Effect of Isocaloric Meals on Postprandial Glycemic and Metabolic Markers in Type 1 Diabetes—A Randomized Crossover Trial
por: Barouti, Afroditi Alexandra, et al.
Publicado: (2023)

α‐Thianthrenium Carbonyl Species: The Equivalent of an α‐Carbonyl Carbocation
por: Jia, Hao, et al.
Publicado: (2022)

Inhibition of LPS-induced production of inflammatory factors in the macrophages by mono-carbonyl analogues of curcumin
por: Liang, Guang, et al.
Publicado: (2009)

Inhibition of Tissue Matrix Metalloproteinases Interferes with Mycobacterium tuberculosis-Induced Granuloma Formation and Reduces Bacterial Load in a Human Lung Tissue Model
por: Parasa, Venkata R., et al.
Publicado: (2017)

Dissecting conjugation and electronic effects on the linear and non-linear optical properties of rhenium(i) carbonyl complexes
por: Fernández-Terán, Ricardo J., et al.
Publicado: (2022)

Riedel’s thyroiditis: clinical presentation, treatment and outcomes
por: Falhammar, Henrik, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8fiff7j8rrn65tqd8lk1olbbf3