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Combined Locked Nucleic Acid Probes and High-Resolution Melting Curve Analysis for Detection of Rifampicin-Resistant Tuberculosis in Northern Thailand

Rifampicin-resistant tuberculosis (RR-TB) has become a major threat globally. This study aims to develop a new assay, RIF-RDp, to enhance the detection of RR-TB based on combined locked nucleic acid (LNA) probes with high-resolution melting curve analysis (HRM). Two new LNA probes were designed to t...

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Detalles Bibliográficos
Autores principales: Thant, Yee Mon, Saikaew, Sukanya, Tharinjaroen, Chayada Sitthidet, Phunpae, Ponrut, Pongsararuk, Rodjana, Preechasuth, Kanya, Butr-Indr, Bordin, Intorasoot, Sorasak, Tragoolpua, Khajornsak, Chaiprasert, Angkana, Wattananandkul, Usanee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600958/
https://www.ncbi.nlm.nih.gov/pubmed/36291996
http://dx.doi.org/10.3390/diagnostics12102307

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