Cation ATPase (ATP4) Orthologue Replacement in the Malaria Parasite Plasmodium knowlesi Reveals Species-Specific Responses to ATP4-Targeting Drugs

Several unrelated classes of antimalarial compounds developed against Plasmodium falciparum target a parasite-specific P-type ATP-dependent Na(+) pump, PfATP4. We have previously shown that other malaria parasite species infecting humans are less susceptible to these compounds. Here, we generated a...

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Detalles Bibliográficos
Autores principales: Mohring, Franziska, van Schalkwyk, Donelly A., Henrici, Ryan C., Blasco, Benjamin, Leroy, Didier, Sutherland, Colin J., Moon, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600963/
https://www.ncbi.nlm.nih.gov/pubmed/36190127
http://dx.doi.org/10.1128/mbio.01178-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600963/
https://www.ncbi.nlm.nih.gov/pubmed/36190127
http://dx.doi.org/10.1128/mbio.01178-22

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