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TRAF3/p38-JNK Signalling Crosstalk with Intracellular-TRAIL/Caspase-10-Induced Apoptosis Accelerates ROS-Driven Cancer Cell-Specific Death by CD40

The capacity to induce tumour-cell specific apoptosis represents the most unique feature of the TNF receptor (TNFR) family member CD40. Recent studies on the signalling events triggered by its membrane-presented ligand CD40L (mCD40L) in normal and malignant epithelial cells have started to unravel a...

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Detalles Bibliográficos
Autores principales: Ibraheem, Khalidah, Yhmed, Albashir M. A., Nasef, Mohamed M., Georgopoulos, Nikolaos T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600997/
https://www.ncbi.nlm.nih.gov/pubmed/36291141
http://dx.doi.org/10.3390/cells11203274