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Association between Dysfunction of the Nucleolar Stress Response and Multidrug Resistance in Pediatric Acute Lymphoblastic Leukemia

SIMPLE SUMMARY: Pediatric patients with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) relapse or are refractory to chemotherapy despite the low frequency of TP53 mutations. The nucleolar stress response is one of the mechanisms that activate P53 by ribosomal protein L11 (RPL11). We hypothe...

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Detalles Bibliográficos
Autores principales:	Nakagawa, Shunsuke, Kawahara, Kohichi, Okamoto, Yasuhiro, Kodama, Yuichi, Nishikawa, Takuro, Kawano, Yoshifumi, Furukawa, Tatsuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601175/ https://www.ncbi.nlm.nih.gov/pubmed/36291909 http://dx.doi.org/10.3390/cancers14205127

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