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Genome Capture Sequencing Selectively Enriches Bacterial DNA and Enables Genome-Wide Measurement of Intrastrain Genetic Diversity in Human Infections

Within-host evolution produces genetic diversity in bacterial strains that cause chronic human infections. However, the lack of facile methods to measure bacterial allelic variation in clinical samples has limited understanding of intrastrain diversity’s effects on disease. Here, we report a new met...

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Detalles Bibliográficos
Autores principales:	Hayden, Hillary S., Joshi, Snehal, Radey, Matthew C., Vo, Anh T., Forsberg, Cara, Morgan, Sarah J., Waalkes, Adam, Holmes, Elizabeth A., Klee, Sara M., Emond, Mary J., Singh, Pradeep K., Salipante, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601202/ https://www.ncbi.nlm.nih.gov/pubmed/36121157 http://dx.doi.org/10.1128/mbio.01424-22

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