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Cannabidiol in Dentistry: A Scoping Review
Cannabidiol (CBD) has been gaining increased attention in contemporary society but seems to have been little explored in dentistry. This scoping review mapped the scientific and technological scenarios related to the use of CBD in dentistry. Peer-reviewed publications were searched in five internati...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601225/ https://www.ncbi.nlm.nih.gov/pubmed/36286003 http://dx.doi.org/10.3390/dj10100193 |
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author | David, Carla Elizalde-Hernández, Alejandro Barboza, Andressa S. Cardoso, Gabriela C. Santos, Mateus B. F. Moraes, Rafael R. |
author_facet | David, Carla Elizalde-Hernández, Alejandro Barboza, Andressa S. Cardoso, Gabriela C. Santos, Mateus B. F. Moraes, Rafael R. |
author_sort | David, Carla |
collection | PubMed |
description | Cannabidiol (CBD) has been gaining increased attention in contemporary society but seems to have been little explored in dentistry. This scoping review mapped the scientific and technological scenarios related to the use of CBD in dentistry. Peer-reviewed publications were searched in five international databases, patents were searched in five technological platforms. In total, 11 articles and 13 patents involving CBD in dentistry-related applications were included. The countries contributing to most articles were Brazil (27.3%) and USA (18.2%). The studies involved experiments on animals (63.6%) and/or using bacteria or cells (36.4%), and no clinical study was found. Three different applications of CBD were observed: periodontal therapy (45.4%), aid for bone regeneration (27.3%), and general use in oral therapies (27.3%). Patent inventors were based in China (53.8%) or USA (46.2%). The patent claims were mainly compositions for oral care, tooth whitening, injury repair, antifungal, anti-inflammatory, and analgesic effects. A total of 76.9% of the patents were filed in association with a company. In general, research suggests that CBD has promising biological properties for applications in dentistry, whereas patents indicate that the current interest of industry relies on compositions for oral care. There appears to be extensive room available for research and technological applications of CBD in dentistry. |
format | Online Article Text |
id | pubmed-9601225 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96012252022-10-27 Cannabidiol in Dentistry: A Scoping Review David, Carla Elizalde-Hernández, Alejandro Barboza, Andressa S. Cardoso, Gabriela C. Santos, Mateus B. F. Moraes, Rafael R. Dent J (Basel) Review Cannabidiol (CBD) has been gaining increased attention in contemporary society but seems to have been little explored in dentistry. This scoping review mapped the scientific and technological scenarios related to the use of CBD in dentistry. Peer-reviewed publications were searched in five international databases, patents were searched in five technological platforms. In total, 11 articles and 13 patents involving CBD in dentistry-related applications were included. The countries contributing to most articles were Brazil (27.3%) and USA (18.2%). The studies involved experiments on animals (63.6%) and/or using bacteria or cells (36.4%), and no clinical study was found. Three different applications of CBD were observed: periodontal therapy (45.4%), aid for bone regeneration (27.3%), and general use in oral therapies (27.3%). Patent inventors were based in China (53.8%) or USA (46.2%). The patent claims were mainly compositions for oral care, tooth whitening, injury repair, antifungal, anti-inflammatory, and analgesic effects. A total of 76.9% of the patents were filed in association with a company. In general, research suggests that CBD has promising biological properties for applications in dentistry, whereas patents indicate that the current interest of industry relies on compositions for oral care. There appears to be extensive room available for research and technological applications of CBD in dentistry. MDPI 2022-10-17 /pmc/articles/PMC9601225/ /pubmed/36286003 http://dx.doi.org/10.3390/dj10100193 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review David, Carla Elizalde-Hernández, Alejandro Barboza, Andressa S. Cardoso, Gabriela C. Santos, Mateus B. F. Moraes, Rafael R. Cannabidiol in Dentistry: A Scoping Review |
title | Cannabidiol in Dentistry: A Scoping Review |
title_full | Cannabidiol in Dentistry: A Scoping Review |
title_fullStr | Cannabidiol in Dentistry: A Scoping Review |
title_full_unstemmed | Cannabidiol in Dentistry: A Scoping Review |
title_short | Cannabidiol in Dentistry: A Scoping Review |
title_sort | cannabidiol in dentistry: a scoping review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601225/ https://www.ncbi.nlm.nih.gov/pubmed/36286003 http://dx.doi.org/10.3390/dj10100193 |
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