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Interferon-Inducible E3 Ligase RNF213 Facilitates Host-Protective Linear and K63-Linked Ubiquitylation of Toxoplasma gondii Parasitophorous Vacuoles

The obligate intracellular protozoan pathogen Toxoplasma gondii infects a wide range of vertebrate hosts and frequently causes zoonotic infections in humans. Whereas infected immunocompetent individuals typically remain asymptomatic, toxoplasmosis in immunocompromised individuals can manifest as a s...

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Detalles Bibliográficos
Autores principales: Hernandez, Dulcemaria, Walsh, Stephen, Saavedra Sanchez, Luz, Dickinson, Mary S., Coers, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601232/
https://www.ncbi.nlm.nih.gov/pubmed/36154443
http://dx.doi.org/10.1128/mbio.01888-22