Cargando…

Interferon-Inducible E3 Ligase RNF213 Facilitates Host-Protective Linear and K63-Linked Ubiquitylation of Toxoplasma gondii Parasitophorous Vacuoles

The obligate intracellular protozoan pathogen Toxoplasma gondii infects a wide range of vertebrate hosts and frequently causes zoonotic infections in humans. Whereas infected immunocompetent individuals typically remain asymptomatic, toxoplasmosis in immunocompromised individuals can manifest as a s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hernandez, Dulcemaria, Walsh, Stephen, Saavedra Sanchez, Luz, Dickinson, Mary S., Coers, Jörn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601232/ https://www.ncbi.nlm.nih.gov/pubmed/36154443 http://dx.doi.org/10.1128/mbio.01888-22

Ejemplares similares

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole
por: Khaminets, Aliaksandr, et al.
Publicado: (2010)

Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPases
por: Martens, Sascha, et al.
Publicado: (2005)

Contribution of the Residual Body in the Spatial Organization of Toxoplasma gondii Tachyzoites within the Parasitophorous Vacuole
por: Muñiz-Hernández, S., et al.
Publicado: (2011)

Ubiquitination of pathogen-containing vacuoles promotes host defense to Chlamydia trachomatis and Toxoplasma gondii
por: Coers, Jörn, et al.
Publicado: (2015)

The Toxoplasma gondii protein ROP2 mediates host organelle association with the parasitophorous vacuole membrane
por: Sinai, Anthony P., et al.
Publicado: (2001)

Toxoplasma gondii excretion of glycolytic products is associated with acidification of the parasitophorous vacuole during parasite egress
por: Huynh, My-Hang, et al.
Publicado: (2022)

Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Regulate Maturation of the Cyst Wall
por: Guevara, Rebekah B., et al.
Publicado: (2020)

Divergent kinase regulates membrane ultrastructure of the Toxoplasma parasitophorous vacuole
por: Beraki, Tsebaot, et al.
Publicado: (2019)

Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole
por: Romano, Julia D., et al.
Publicado: (2013)

Identification of a novel protein complex essential for effector translocation across the parasitophorous vacuole membrane of Toxoplasma gondii
por: Marino, Nicole D., et al.
Publicado: (2018)

Toxoplasma gondii PPM3C, a secreted protein phosphatase, affects parasitophorous vacuole effector export
por: Mayoral, Joshua, et al.
Publicado: (2020)

Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii
por: Johnston, Ashleigh C., et al.
Publicado: (2016)

Rhoptry kinase protein 39 (ROP39) is a novel factor that recruits host mitochondria to the parasitophorous vacuole of Toxoplasma gondii
por: Fukumoto, Junpei, et al.
Publicado: (2021)

The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm
Publicado: (1994)

Host ER–parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii–infected dendritic cells
por: Goldszmid, Romina S., et al.
Publicado: (2009)

Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death
por: Zhao, Yang O., et al.
Publicado: (2009)

Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Orchestrate Chronic Infection and GRA12 Underpins Resistance to Host Gamma Interferon
por: Fox, Barbara A., et al.
Publicado: (2019)

Proximity-Labeling Reveals Novel Host and Parasite Proteins at the Toxoplasma Parasitophorous Vacuole Membrane
por: Cygan, Alicja M., et al.
Publicado: (2021)

Culture of mouse peritoneal macrophages with mouse serum induces lipid bodies that associate with the parasitophorous vacuole and decrease their microbicidal capacity against Toxoplasma gondii
por: Mota, Laura Azeredo Miranda, et al.
Publicado: (2014)

MMD-associated RNF213 SNPs encode dominant-negative alleles that globally impair ubiquitylation
por: Bhardwaj, Abhishek, et al.
Publicado: (2022)

Coimmunoprecipitation with MYR1 Identifies Three Additional Proteins within the Toxoplasma gondii Parasitophorous Vacuole Required for Translocation of Dense Granule Effectors into Host Cells
por: Cygan, Alicja M., et al.
Publicado: (2020)

The Leishmania Parasitophorous Vacuole Membrane at the Parasite-Host Interface
por: Young, Jeffrey, et al.
Publicado: (2019)

In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis
por: Nadipuram, Santhosh M., et al.
Publicado: (2016)

Toxoplasma Does Not Secrete the GRA16 and GRA24 Effectors Beyond the Parasitophorous Vacuole Membrane of Tissue Cysts
por: Krishnamurthy, Shruthi, et al.
Publicado: (2018)

Host MOSPD2 enrichment at the parasitophorous vacuole membrane varies between Toxoplasma strains and involves complex interactions
por: Ferrel, Abel, et al.
Publicado: (2023)

The Parasitic Intracellular Lifestyle of Trypanosomatids: Parasitophorous Vacuole Development and Survival
por: Batista, Marina Ferreira, et al.
Publicado: (2020)

The emerging role of E3 ubiquitin ligase RNF213 as an antimicrobial host determinant
por: Zhang, Yulu, et al.
Publicado: (2023)

Differential regulation of RNF8-mediated Lys48- and Lys63-based poly-ubiquitylation
por: Lok, Gabriel Tsz-Mei, et al.
Publicado: (2012)

UBC13 is an RNF213‐associated E2 ubiquitin‐conjugating enzyme, and Lysine 63‐linked ubiquitination by the RNF213‐UBC13 axis is responsible for angiogenic activity
por: Habu, Toshiyuki, et al.
Publicado: (2021)

Plasmodium Protease ROM1 Is Important for Proper Formation of the Parasitophorous Vacuole
por: Vera, Iset Medina, et al.
Publicado: (2011)

Host Kinase Activity is Required for Coxiella burnetii Parasitophorous Vacuole Formation
por: Hussain, S. Kauser, et al.
Publicado: (2010)

The Diverse and Dynamic Nature of Leishmania Parasitophorous Vacuoles Studied by Multidimensional Imaging
por: Real, Fernando, et al.
Publicado: (2012)

Trypanosoma cruzi: Entry into Mammalian Host Cells and Parasitophorous Vacuole Formation
por: Barrias, Emile Santos, et al.
Publicado: (2013)

Leishmania amazonensis Engages CD36 to Drive Parasitophorous Vacuole Maturation
por: Okuda, Kendi, et al.
Publicado: (2016)

BioID Reveals Novel Proteins of the Plasmodium Parasitophorous Vacuole Membrane
por: Schnider, Cilly Bernardette, et al.
Publicado: (2018)

Inverted recruitment of autophagy proteins to the Plasmodium berghei parasitophorous vacuole membrane
por: Schmuckli-Maurer, Jacqueline, et al.
Publicado: (2017)

Neuromuscular regulation in zebrafish by a large AAA+ ATPase/ubiquitin ligase, mysterin/RNF213
por: Kotani, Yuri, et al.
Publicado: (2015)

Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It
por: Virreira Winter, Sebastian, et al.
Publicado: (2011)

Structural basis of membrane recognition of Toxoplasma gondii vacuole by Irgb6
por: Saijo-Hamano, Yumiko, et al.
Publicado: (2021)

A Plasmodium Phospholipase Is Involved in Disruption of the Liver Stage Parasitophorous Vacuole Membrane
por: Burda, Paul-Christian, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4idsmdorp440jju9m60tdsajqs