Cargando…

High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland

Background: Hypovitaminosis D is common in populations with obesity. This study aimed at assessing (1) the prevalence of hypovitaminosis D and (2) the associations between vitamin D levels and cardiovascular risk factors in adolescents attending a reference centre for the treatment of obesity. Desig...

Descripción completa

Detalles Bibliográficos
Autores principales: Patriota, Pollyanna, Borloz, Sylvie, Ruiz, Inge, Bouthors, Thérèse, Rezzi, Serge, Marques-Vidal, Pedro, Hauschild, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601272/
https://www.ncbi.nlm.nih.gov/pubmed/36291463
http://dx.doi.org/10.3390/children9101527
_version_ 1784817020097789952
author Patriota, Pollyanna
Borloz, Sylvie
Ruiz, Inge
Bouthors, Thérèse
Rezzi, Serge
Marques-Vidal, Pedro
Hauschild, Michael
author_facet Patriota, Pollyanna
Borloz, Sylvie
Ruiz, Inge
Bouthors, Thérèse
Rezzi, Serge
Marques-Vidal, Pedro
Hauschild, Michael
author_sort Patriota, Pollyanna
collection PubMed
description Background: Hypovitaminosis D is common in populations with obesity. This study aimed at assessing (1) the prevalence of hypovitaminosis D and (2) the associations between vitamin D levels and cardiovascular risk factors in adolescents attending a reference centre for the treatment of obesity. Design: Cross-sectional pilot study conducted in the paediatric obesity unit of the Lausanne university hospital, Switzerland. Methods: Participants were considered eligible if they (1) were aged between 10 to 16.9 years and (2) consulted between 2017 and 2021. Participants were excluded if (1) they lacked vitamin D measurements or (2) the vitamin D measurement was performed one month after the base anthropometric assessment. Hypovitaminosis D was considered if the vitamin D level was <30 ng/mL (<75 nmol/L). Severe obesity was defined as a BMI z-score > 3 SD. Results: We included 52 adolescents (31% girls, mean age 13 ± 2 years, 33% with severe obesity). The prevalence of hypovitaminosis D was 87.5% in girls and 88.9% in boys. The vitamin D levels were inversely associated with BMI, Spearman r and 95% CI: −0.286 (−0.555; −0.017), p = 0.037; they were not associated with the BMI z-score: −0.052 (−0.327; 0.224), p = 0.713. The vitamin D levels were negatively associated with the parathormone levels (−0.353 (−0.667; −0.039), p = 0.028) and positively associated with the calcium levels (0.385 (0.061; 0.708), p = 0.020), while no association was found between vitamin D levels and blood pressure and lipid or glucose levels. Conclusion: almost 9 out of 10 adolescents with obesity in our cohort presented with hypovitaminosis D. Hypovitaminosis D does not seem to be associated with a higher cardiovascular risk profile in this group.
format Online
Article
Text
id pubmed-9601272
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96012722022-10-27 High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland Patriota, Pollyanna Borloz, Sylvie Ruiz, Inge Bouthors, Thérèse Rezzi, Serge Marques-Vidal, Pedro Hauschild, Michael Children (Basel) Article Background: Hypovitaminosis D is common in populations with obesity. This study aimed at assessing (1) the prevalence of hypovitaminosis D and (2) the associations between vitamin D levels and cardiovascular risk factors in adolescents attending a reference centre for the treatment of obesity. Design: Cross-sectional pilot study conducted in the paediatric obesity unit of the Lausanne university hospital, Switzerland. Methods: Participants were considered eligible if they (1) were aged between 10 to 16.9 years and (2) consulted between 2017 and 2021. Participants were excluded if (1) they lacked vitamin D measurements or (2) the vitamin D measurement was performed one month after the base anthropometric assessment. Hypovitaminosis D was considered if the vitamin D level was <30 ng/mL (<75 nmol/L). Severe obesity was defined as a BMI z-score > 3 SD. Results: We included 52 adolescents (31% girls, mean age 13 ± 2 years, 33% with severe obesity). The prevalence of hypovitaminosis D was 87.5% in girls and 88.9% in boys. The vitamin D levels were inversely associated with BMI, Spearman r and 95% CI: −0.286 (−0.555; −0.017), p = 0.037; they were not associated with the BMI z-score: −0.052 (−0.327; 0.224), p = 0.713. The vitamin D levels were negatively associated with the parathormone levels (−0.353 (−0.667; −0.039), p = 0.028) and positively associated with the calcium levels (0.385 (0.061; 0.708), p = 0.020), while no association was found between vitamin D levels and blood pressure and lipid or glucose levels. Conclusion: almost 9 out of 10 adolescents with obesity in our cohort presented with hypovitaminosis D. Hypovitaminosis D does not seem to be associated with a higher cardiovascular risk profile in this group. MDPI 2022-10-06 /pmc/articles/PMC9601272/ /pubmed/36291463 http://dx.doi.org/10.3390/children9101527 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Patriota, Pollyanna
Borloz, Sylvie
Ruiz, Inge
Bouthors, Thérèse
Rezzi, Serge
Marques-Vidal, Pedro
Hauschild, Michael
High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland
title High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland
title_full High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland
title_fullStr High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland
title_full_unstemmed High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland
title_short High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland
title_sort high prevalence of hypovitaminosis d in adolescents attending a reference centre for the treatment of obesity in switzerland
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601272/
https://www.ncbi.nlm.nih.gov/pubmed/36291463
http://dx.doi.org/10.3390/children9101527
work_keys_str_mv AT patriotapollyanna highprevalenceofhypovitaminosisdinadolescentsattendingareferencecentreforthetreatmentofobesityinswitzerland
AT borlozsylvie highprevalenceofhypovitaminosisdinadolescentsattendingareferencecentreforthetreatmentofobesityinswitzerland
AT ruizinge highprevalenceofhypovitaminosisdinadolescentsattendingareferencecentreforthetreatmentofobesityinswitzerland
AT bouthorstherese highprevalenceofhypovitaminosisdinadolescentsattendingareferencecentreforthetreatmentofobesityinswitzerland
AT rezziserge highprevalenceofhypovitaminosisdinadolescentsattendingareferencecentreforthetreatmentofobesityinswitzerland
AT marquesvidalpedro highprevalenceofhypovitaminosisdinadolescentsattendingareferencecentreforthetreatmentofobesityinswitzerland
AT hauschildmichael highprevalenceofhypovitaminosisdinadolescentsattendingareferencecentreforthetreatmentofobesityinswitzerland