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To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks

Early work by Muller and McClintock discovered that the physical ends of linear chromosomes, named telomeres, possess an inherent ability to escape unwarranted fusions. Since then, extensive research has shown that this special feature relies on specialized proteins and structural properties that co...

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Detalles Bibliográficos
Autores principales: Casari, Erika, Gnugnoli, Marco, Rinaldi, Carlo, Pizzul, Paolo, Colombo, Chiara Vittoria, Bonetti, Diego, Longhese, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601279/
https://www.ncbi.nlm.nih.gov/pubmed/36291091
http://dx.doi.org/10.3390/cells11203224