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To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks
Early work by Muller and McClintock discovered that the physical ends of linear chromosomes, named telomeres, possess an inherent ability to escape unwarranted fusions. Since then, extensive research has shown that this special feature relies on specialized proteins and structural properties that co...
Autores principales: | Casari, Erika, Gnugnoli, Marco, Rinaldi, Carlo, Pizzul, Paolo, Colombo, Chiara Vittoria, Bonetti, Diego, Longhese, Maria Pia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601279/ https://www.ncbi.nlm.nih.gov/pubmed/36291091 http://dx.doi.org/10.3390/cells11203224 |
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