Sorting nexin 17 increases low-density lipoprotein receptor-related protein 4 membrane expression: A novel mechanism of acetylcholine receptor aggregation in myasthenia gravis

Myasthenia gravis (MG) is characterized by autoimmune damage to the postsynaptic membrane of the neuromuscular junction (NMJ) with impaired postsynaptic acetylcholine receptor (AChR) aggregation. Low-density lipoprotein receptor-related protein 4 (LRP4) plays an important role in AChR aggregation at...

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Detalles Bibliográficos
Autores principales: He, Xiaoxiao, Zhou, Shuxian, Ji, Ying, Zhang, Yingna, Lv, Jie, Quan, Shangkun, Zhang, Jing, Zhao, Xue, Cui, Weike, Li, Wenbo, Liu, Peipei, Zhang, Linyuan, Shen, Tong, Fang, Hua, Yang, Junhong, Zhang, Yunke, Cui, Xinzheng, Zhang, Qingyong, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601310/
https://www.ncbi.nlm.nih.gov/pubmed/36311763
http://dx.doi.org/10.3389/fimmu.2022.916098

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