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The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion

The development of adhesive hydrogel materials has brought numerous advances to biomedical engineering. Hydrogel adhesion has drawn much attention in research and applications. In this paper, the study of hydrogel adhesion is no longer limited to the surface of hydrogels. Here, the effect of the int...

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Detalles Bibliográficos
Autores principales: Li, Zhangkang, Yu, Cheng, Kumar, Hitendra, He, Xiao, Lu, Qingye, Bai, Huiyu, Kim, Keekyoung, Hu, Jinguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601496/
https://www.ncbi.nlm.nih.gov/pubmed/36286183
http://dx.doi.org/10.3390/gels8100682
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author Li, Zhangkang
Yu, Cheng
Kumar, Hitendra
He, Xiao
Lu, Qingye
Bai, Huiyu
Kim, Keekyoung
Hu, Jinguang
author_facet Li, Zhangkang
Yu, Cheng
Kumar, Hitendra
He, Xiao
Lu, Qingye
Bai, Huiyu
Kim, Keekyoung
Hu, Jinguang
author_sort Li, Zhangkang
collection PubMed
description The development of adhesive hydrogel materials has brought numerous advances to biomedical engineering. Hydrogel adhesion has drawn much attention in research and applications. In this paper, the study of hydrogel adhesion is no longer limited to the surface of hydrogels. Here, the effect of the internal crosslinking degree of hydrogels prepared by different methods on hydrogel adhesion was explored to find the generality. The results show that with the increase in crosslinking degree, the hydrogel adhesion decreased significantly due to the limitation of segment mobility. Moreover, two simple strategies to improve hydrogel adhesion generated by hydrogen bonding were proposed. One was to keep the functional groups used for hydrogel adhesion and the other was to enhance the flexibility of polymer chains that make up hydrogels. We hope this study can provide another approach for improving the hydrogel adhesion generated by hydrogen bonding.
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spelling pubmed-96014962022-10-27 The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion Li, Zhangkang Yu, Cheng Kumar, Hitendra He, Xiao Lu, Qingye Bai, Huiyu Kim, Keekyoung Hu, Jinguang Gels Article The development of adhesive hydrogel materials has brought numerous advances to biomedical engineering. Hydrogel adhesion has drawn much attention in research and applications. In this paper, the study of hydrogel adhesion is no longer limited to the surface of hydrogels. Here, the effect of the internal crosslinking degree of hydrogels prepared by different methods on hydrogel adhesion was explored to find the generality. The results show that with the increase in crosslinking degree, the hydrogel adhesion decreased significantly due to the limitation of segment mobility. Moreover, two simple strategies to improve hydrogel adhesion generated by hydrogen bonding were proposed. One was to keep the functional groups used for hydrogel adhesion and the other was to enhance the flexibility of polymer chains that make up hydrogels. We hope this study can provide another approach for improving the hydrogel adhesion generated by hydrogen bonding. MDPI 2022-10-21 /pmc/articles/PMC9601496/ /pubmed/36286183 http://dx.doi.org/10.3390/gels8100682 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Li, Zhangkang
Yu, Cheng
Kumar, Hitendra
He, Xiao
Lu, Qingye
Bai, Huiyu
Kim, Keekyoung
Hu, Jinguang
The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion
title The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion
title_full The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion
title_fullStr The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion
title_full_unstemmed The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion
title_short The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion
title_sort effect of crosslinking degree of hydrogels on hydrogel adhesion
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601496/
https://www.ncbi.nlm.nih.gov/pubmed/36286183
http://dx.doi.org/10.3390/gels8100682
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