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Hereditary Breast and Ovarian Cancer Service in Sparsely Populated Western Pomerania

The German Consortium Hereditary Breast and Ovarian Cancer (GC-HBOC) consists of 23 academic centers striving to provide high-quality regional care for affected individuals and healthy at-risk family members. According to the standard operating procedures defined by the GC-HBOC, a Familial Breast an...

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Autores principales: Felbor, Ute, Bülow, Robin, Schmutzler, Rita K., Rath, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601587/
https://www.ncbi.nlm.nih.gov/pubmed/36292468
http://dx.doi.org/10.3390/healthcare10102021
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author Felbor, Ute
Bülow, Robin
Schmutzler, Rita K.
Rath, Matthias
author_facet Felbor, Ute
Bülow, Robin
Schmutzler, Rita K.
Rath, Matthias
author_sort Felbor, Ute
collection PubMed
description The German Consortium Hereditary Breast and Ovarian Cancer (GC-HBOC) consists of 23 academic centers striving to provide high-quality regional care for affected individuals and healthy at-risk family members. According to the standard operating procedures defined by the GC-HBOC, a Familial Breast and Ovarian Cancer Center was implemented at the University Medicine Greifswald over a four-year period from 2018 to 2021, despite the COVID-19 pandemic. Genetic analyses were performed in a total of 658 individuals, including 41 males, which paved the way to local annual risk-adapted breast cancer surveillance for 91 women and prophylactic surgery for 34 women in 2021. Our experience in the North Eastern part of Germany demonstrates that it is possible to establish a high-risk breast and ovarian cancer service even in a sparsely populated region. Major facilitators are the interdisciplinary collaboration of dedicated local experts, the support of the GC-HBOC, fruitful clinical and scientific cooperations and the use of technical improvements. As a blueprint, our project report may help to further expand the network of specialized and knowledge-generating care for HBOC families.
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spelling pubmed-96015872022-10-27 Hereditary Breast and Ovarian Cancer Service in Sparsely Populated Western Pomerania Felbor, Ute Bülow, Robin Schmutzler, Rita K. Rath, Matthias Healthcare (Basel) Project Report The German Consortium Hereditary Breast and Ovarian Cancer (GC-HBOC) consists of 23 academic centers striving to provide high-quality regional care for affected individuals and healthy at-risk family members. According to the standard operating procedures defined by the GC-HBOC, a Familial Breast and Ovarian Cancer Center was implemented at the University Medicine Greifswald over a four-year period from 2018 to 2021, despite the COVID-19 pandemic. Genetic analyses were performed in a total of 658 individuals, including 41 males, which paved the way to local annual risk-adapted breast cancer surveillance for 91 women and prophylactic surgery for 34 women in 2021. Our experience in the North Eastern part of Germany demonstrates that it is possible to establish a high-risk breast and ovarian cancer service even in a sparsely populated region. Major facilitators are the interdisciplinary collaboration of dedicated local experts, the support of the GC-HBOC, fruitful clinical and scientific cooperations and the use of technical improvements. As a blueprint, our project report may help to further expand the network of specialized and knowledge-generating care for HBOC families. MDPI 2022-10-13 /pmc/articles/PMC9601587/ /pubmed/36292468 http://dx.doi.org/10.3390/healthcare10102021 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Project Report
Felbor, Ute
Bülow, Robin
Schmutzler, Rita K.
Rath, Matthias
Hereditary Breast and Ovarian Cancer Service in Sparsely Populated Western Pomerania
title Hereditary Breast and Ovarian Cancer Service in Sparsely Populated Western Pomerania
title_full Hereditary Breast and Ovarian Cancer Service in Sparsely Populated Western Pomerania
title_fullStr Hereditary Breast and Ovarian Cancer Service in Sparsely Populated Western Pomerania
title_full_unstemmed Hereditary Breast and Ovarian Cancer Service in Sparsely Populated Western Pomerania
title_short Hereditary Breast and Ovarian Cancer Service in Sparsely Populated Western Pomerania
title_sort hereditary breast and ovarian cancer service in sparsely populated western pomerania
topic Project Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601587/
https://www.ncbi.nlm.nih.gov/pubmed/36292468
http://dx.doi.org/10.3390/healthcare10102021
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