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Genetic Polymorphism of 27 Y-STR Loci in the Western Kazakh Tribes from Kazakhstan and Karakalpakstan, Uzbekistan

Data on the genetic polymorphism of 27 Y-STR in Kazakhs of the Junior Zhuz has been presented and analyzed in relation to forensic features. A total of 464 representatives of the Western Kazakh tribes of Kazakhstan (Western Kazakhs, n = 405) and Uzbekistan (Karakalpakstan Kazakhs, n = 59) were exami...

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Autores principales: Ashirbekov, Yeldar, Sabitov, Zhaxylyk, Aidarov, Baglan, Abaildayev, Arman, Junissova, Zukhra, Cherusheva, Alena, Saidamarova, Viktoriya V., Sharipov, Kamalidin, Ramankulov, Yerlan, Zhabagin, Maxat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601638/
https://www.ncbi.nlm.nih.gov/pubmed/36292713
http://dx.doi.org/10.3390/genes13101826
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author Ashirbekov, Yeldar
Sabitov, Zhaxylyk
Aidarov, Baglan
Abaildayev, Arman
Junissova, Zukhra
Cherusheva, Alena
Saidamarova, Viktoriya V.
Sharipov, Kamalidin
Ramankulov, Yerlan
Zhabagin, Maxat
author_facet Ashirbekov, Yeldar
Sabitov, Zhaxylyk
Aidarov, Baglan
Abaildayev, Arman
Junissova, Zukhra
Cherusheva, Alena
Saidamarova, Viktoriya V.
Sharipov, Kamalidin
Ramankulov, Yerlan
Zhabagin, Maxat
author_sort Ashirbekov, Yeldar
collection PubMed
description Data on the genetic polymorphism of 27 Y-STR in Kazakhs of the Junior Zhuz has been presented and analyzed in relation to forensic features. A total of 464 representatives of the Western Kazakh tribes of Kazakhstan (Western Kazakhs, n = 405) and Uzbekistan (Karakalpakstan Kazakhs, n = 59) were examined by the Yfiler Plus set. The data are available in the YHRD under accession numbers YA006010 and YA006009. Genetic analysis (AMOVA and MDS) did not show significant differences between the two groups (Kazakhstan and Karakalpakstan Kazakhs) in terms of Y-chromosome diversity. Both groups are characterized by haplogroup C2a1a2 as a founder effect, which dominated two of the three tribes: Alimuly (67%), Baiuly (74.6%), and Zhetiru (25.8%). At the same time, the phylogenetic network for each tribe found its own clusters within C2a1a2. Western Kazakhs and Karakalpakstan Kazakhs present high values of unique haplotypes (84.44% and 96.61%), discrimination capacity (90.37% and 98.30%), and haplotype diversity (0.9991 and 0.9994). A set of 27 Y-STR loci distinguishes closely related individuals within the Western Kazakh tribes quite well. It is suitable for forensic application, and is also optimal for population genetics studies.
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spelling pubmed-96016382022-10-27 Genetic Polymorphism of 27 Y-STR Loci in the Western Kazakh Tribes from Kazakhstan and Karakalpakstan, Uzbekistan Ashirbekov, Yeldar Sabitov, Zhaxylyk Aidarov, Baglan Abaildayev, Arman Junissova, Zukhra Cherusheva, Alena Saidamarova, Viktoriya V. Sharipov, Kamalidin Ramankulov, Yerlan Zhabagin, Maxat Genes (Basel) Brief Report Data on the genetic polymorphism of 27 Y-STR in Kazakhs of the Junior Zhuz has been presented and analyzed in relation to forensic features. A total of 464 representatives of the Western Kazakh tribes of Kazakhstan (Western Kazakhs, n = 405) and Uzbekistan (Karakalpakstan Kazakhs, n = 59) were examined by the Yfiler Plus set. The data are available in the YHRD under accession numbers YA006010 and YA006009. Genetic analysis (AMOVA and MDS) did not show significant differences between the two groups (Kazakhstan and Karakalpakstan Kazakhs) in terms of Y-chromosome diversity. Both groups are characterized by haplogroup C2a1a2 as a founder effect, which dominated two of the three tribes: Alimuly (67%), Baiuly (74.6%), and Zhetiru (25.8%). At the same time, the phylogenetic network for each tribe found its own clusters within C2a1a2. Western Kazakhs and Karakalpakstan Kazakhs present high values of unique haplotypes (84.44% and 96.61%), discrimination capacity (90.37% and 98.30%), and haplotype diversity (0.9991 and 0.9994). A set of 27 Y-STR loci distinguishes closely related individuals within the Western Kazakh tribes quite well. It is suitable for forensic application, and is also optimal for population genetics studies. MDPI 2022-10-09 /pmc/articles/PMC9601638/ /pubmed/36292713 http://dx.doi.org/10.3390/genes13101826 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Ashirbekov, Yeldar
Sabitov, Zhaxylyk
Aidarov, Baglan
Abaildayev, Arman
Junissova, Zukhra
Cherusheva, Alena
Saidamarova, Viktoriya V.
Sharipov, Kamalidin
Ramankulov, Yerlan
Zhabagin, Maxat
Genetic Polymorphism of 27 Y-STR Loci in the Western Kazakh Tribes from Kazakhstan and Karakalpakstan, Uzbekistan
title Genetic Polymorphism of 27 Y-STR Loci in the Western Kazakh Tribes from Kazakhstan and Karakalpakstan, Uzbekistan
title_full Genetic Polymorphism of 27 Y-STR Loci in the Western Kazakh Tribes from Kazakhstan and Karakalpakstan, Uzbekistan
title_fullStr Genetic Polymorphism of 27 Y-STR Loci in the Western Kazakh Tribes from Kazakhstan and Karakalpakstan, Uzbekistan
title_full_unstemmed Genetic Polymorphism of 27 Y-STR Loci in the Western Kazakh Tribes from Kazakhstan and Karakalpakstan, Uzbekistan
title_short Genetic Polymorphism of 27 Y-STR Loci in the Western Kazakh Tribes from Kazakhstan and Karakalpakstan, Uzbekistan
title_sort genetic polymorphism of 27 y-str loci in the western kazakh tribes from kazakhstan and karakalpakstan, uzbekistan
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601638/
https://www.ncbi.nlm.nih.gov/pubmed/36292713
http://dx.doi.org/10.3390/genes13101826
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