Cargando…

Single Cell RNA-Seq Identifies Immune-Related Prognostic Model and Key Signature-SPP1 in Pancreatic Ductal Adenocarcinoma

There are no reliable biomarkers for early diagnosis or prognosis evaluation in pancreatic ductal adenocarcinoma (PDAC). Multiple scRNA-seq datasets for PDAC were retrieved from online databases and combined with scRNA-seq results from our previous study. The malignant ductal cells were identified t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Kai, Wang, Qi, Liu, Xinxin, Wang, Feng, Ma, Yongsu, Zhang, Shupeng, Shao, Zhijiang, Yang, Yinmo, Tian, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601640/ https://www.ncbi.nlm.nih.gov/pubmed/36292645 http://dx.doi.org/10.3390/genes13101760

Ejemplares similares

Development and validation of prognostic and diagnostic model for pancreatic ductal adenocarcinoma based on scRNA-seq and bulk-seq datasets
por: Chen, Kai, et al.
Publicado: (2021)

Predictive Model of Early Death of Resectable Pancreatic Ductal Adenocarcinoma After Curative Resection: A SEER-Based Study
por: Liu, Weikang, et al.
Publicado: (2022)

Single-cell RNA-seq reveals dynamic change in tumor microenvironment during pancreatic ductal adenocarcinoma malignant progression
por: Chen, Kai, et al.
Publicado: (2021)

Safety evaluation of early drain removal following pancreaticoduodenectomy: A single-center retrospective cohort study
por: Xie, Xuehai, et al.
Publicado: (2022)

Validation and modification of the AJCC 8th TNM staging system for pancreatic ductal adenocarcinoma in a Chinese cohort: A nationwide pancreas data center analysis
por: Hu, Hao, et al.
Publicado: (2021)

Establishing and validating an ADCP-related prognostic signature in pancreatic ductal adenocarcinoma
por: Zhang, Deyu, et al.
Publicado: (2022)

Prognostic Fifteen-Gene Signature for Early Stage Pancreatic Ductal Adenocarcinoma
por: Chen, Dung-Tsa, et al.
Publicado: (2015)

Novel prognostic gene signature for pancreatic ductal adenocarcinoma based on hypoxia
por: Ren, Min, et al.
Publicado: (2023)

Deciphering the Prognostic Implications of the Components and Signatures in the Immune Microenvironment of Pancreatic Ductal Adenocarcinoma
por: Tang, Rong, et al.
Publicado: (2021)

Surgical options for control of abdominal pain in chronic pancreatitis patients
por: Tian, Xiaodong, et al.
Publicado: (2019)

Development and Verification of the Hypoxia- and Immune-Associated Prognostic Signature for Pancreatic Ductal Adenocarcinoma
por: Chen, Dongjie, et al.
Publicado: (2021)

Construction of a prognostic prediction system for pancreatic ductal adenocarcinoma to investigate the key prognostic genes
por: Zheng, Bingli, et al.
Publicado: (2018)

Circular RNA Signature Predicts Gemcitabine Resistance of Pancreatic Ductal Adenocarcinoma
por: Shao, Feng, et al.
Publicado: (2018)

Five key lncRNAs considered as prognostic targets for predicting pancreatic ductal adenocarcinoma
por: Song, Jukun, et al.
Publicado: (2018)

Expression of SNAIL in accompanying PanIN is a key prognostic indicator in pancreatic ductal adenocarcinomas
por: Fujiwara, Sho, et al.
Publicado: (2019)

Identification of Key Prognostic Biomarker and Its Correlation with Immune Infiltrates in Pancreatic Ductal Adenocarcinoma
por: Luan, Hong, et al.
Publicado: (2020)

Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma
por: Hu, Dingyuan, et al.
Publicado: (2018)

Metabolic detection and systems analyses of pancreatic ductal adenocarcinoma through machine learning, lipidomics, and multi-omics
por: Wang, Guangxi, et al.
Publicado: (2021)

Genome-Wide Profiling Reveals the Landscape of Prognostic Alternative Splicing Signatures in Pancreatic Ductal Adenocarcinoma
por: Yang, Chengkun, et al.
Publicado: (2019)

Key drug-targeting genes in pancreatic ductal adenocarcinoma
por: Sakharkar, Meena Kishore, et al.
Publicado: (2021)

The limits of molecular signatures for pancreatic ductal adenocarcinoma subtyping
por: Lautizi, Manuela, et al.
Publicado: (2022)

A Long Non-coding RNA Signature to Improve Prognostic Prediction of Pancreatic Ductal Adenocarcinoma
por: Zhou, Chenhao, et al.
Publicado: (2019)

Prognostic Significance of Maspin in Pancreatic Ductal Adenocarcinoma
por: Lim, Yun Jeong, et al.
Publicado: (2004)

An Automated Prognostic Model for Pancreatic Ductal Adenocarcinoma
por: Vezakis, Ioannis, et al.
Publicado: (2023)

Prognostic Biomarkers for Pancreatic Ductal Adenocarcinoma: An Umbrella Review
por: Wang, Yizhi, et al.
Publicado: (2020)

The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma
por: Wang, Lai Mun, et al.
Publicado: (2015)

Immune profiling and prognostic model of pancreatic cancer using quantitative pathology and single-cell RNA sequencing
por: Chen, Kai, et al.
Publicado: (2023)

Glycolysis-Related Gene Expression Profiling Screen for Prognostic Risk Signature of Pancreatic Ductal Adenocarcinoma
por: Song, Wenjing, et al.
Publicado: (2021)

A novel messenger RNA signature as a prognostic biomarker for predicting relapse in pancreatic ductal adenocarcinoma
por: Shi, Guodong, et al.
Publicado: (2017)

Ion Channel Signature in Healthy Pancreas and Pancreatic Ductal Adenocarcinoma
por: Schnipper, Julie, et al.
Publicado: (2020)

Prognostic relevance of lactate dehydrogenase in advanced pancreatic ductal adenocarcinoma patients
por: Xiao, Yuanyuan, et al.
Publicado: (2017)

Prognostic Value of VEGF in Human Pancreatic Ductal Adenocarcinoma
por: Lim, Yun Jeong, et al.
Publicado: (2004)

Desmogleins as prognostic biomarkers in resected pancreatic ductal adenocarcinoma
por: Ormanns, Steffen, et al.
Publicado: (2015)

Pancreatic ductal adenocarcinoma: Prognostic indicators of advanced disease
por: Kruger, Deirdré, et al.
Publicado: (2022)

Metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis
por: Mayerle, Julia, et al.
Publicado: (2018)

Prognostic Nomogram for Patients With Pancreatic Ductal Adenocarcinoma of Pancreatic Head After Pancreaticoduodenectomy
por: Zhuang, Hongkai, et al.
Publicado: (2021)

Development and validation of a cancer stem cell-related signature for prognostic prediction in pancreatic ductal adenocarcinoma
por: Feng, Zengyu, et al.
Publicado: (2020)

Development and Validation of a 7-Gene Prognostic Signature to Improve Survival Prediction in Pancreatic Ductal Adenocarcinoma
por: Feng, Zengyu, et al.
Publicado: (2021)

Establishment and validation of a prognostic signature for pancreatic ductal adenocarcinoma based on lactate metabolism-related genes
por: Huang, Xin, et al.
Publicado: (2023)

Potential prognostic biomarkers in pancreatic juice of resectable pancreatic ductal adenocarcinoma
por: Agrawal, Shefali
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_usog58e807h7cq7ivnbnpjuf7q