Cargando…
The Light Chain Domain and Especially the C-Terminus of Receptor-Binding Domain of the Botulinum Neurotoxin (BoNT) Are the Hotspots for Amino Acid Variability and Toxin Type Diversity
Botulinum neurotoxins (BoNT) are the most potent toxins in the world. They are produced by a few dozens of strains within several clostridial species. The toxin that they produce can cause botulism, a flaccid paralysis in humans and other animals. With seven established serologically different types...
Autores principales: | Tian, Renmao, Widel, Melissa, Imanian, Behzad |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601653/ https://www.ncbi.nlm.nih.gov/pubmed/36292800 http://dx.doi.org/10.3390/genes13101915 |
Ejemplares similares
-
Navigating the Complexities Involving the Identification of Botulinum Neurotoxins (BoNTs) and the Taxonomy of BoNT-Producing Clostridia
por: Smith, Theresa J., et al.
Publicado: (2023) -
Botulinum Neurotoxins (BoNTs)—Antibody and Vaccine
por: Lou, Jianlong, et al.
Publicado: (2018) -
Botulinum neurotoxin (BoNT) treatment in functional movement disorders: long-term follow-up
por: Dreissen, Yasmine EM, et al.
Publicado: (2020) -
Preclinical Evidence for the Role of Botulinum Neurotoxin A (BoNT/A) in the Treatment of Peripheral Nerve Injury
por: Adler, Michael, et al.
Publicado: (2022) -
Recombinant Botulinum Neurotoxin Hc Subunit (BoNT Hc) and Catalytically Inactive Clostridium botulinum Holoproteins (ciBoNT HPs) as Vaccine Candidates for the Prevention of Botulism
por: Webb, Robert P., et al.
Publicado: (2017)