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Estimating conformational heterogeneity of tryptophan synthase with a template‐based Alphafold2 approach
The three‐dimensional structure of the enzymes provides very relevant information on the arrangement of the catalytic machinery and structural elements gating the active site pocket. The recent success of the neural network Alphafold2 in predicting the folded structure of proteins from the primary s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601780/ https://www.ncbi.nlm.nih.gov/pubmed/36173176 http://dx.doi.org/10.1002/pro.4426 |