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Uncovering the promiscuous activity of IL‐6 proteins: A multi‐dimensional analysis of phylogeny, classification and residue conservation

The IL‐6 family of cytokines, known for their pleiotropic behavior, share binding to the gp130 receptor for signal transduction with the necessity to bind other receptors. Leukemia inhibitory factor receptor is triggered by the IL‐6 family proteins: leukemia inhibitory factor (LIF), oncostatin‐M (OS...

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Detalles Bibliográficos
Autores principales:	da Costa, André, Franco‐Duarte, Ricardo, Machado, Raul, Gomes, Andreia C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2022
Materias:	Full‐length Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601804/ https://www.ncbi.nlm.nih.gov/pubmed/36222303 http://dx.doi.org/10.1002/pro.4469

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