A Novel Framework for Analysis of the Shared Genetic Background of Correlated Traits

We propose a novel effective framework for the analysis of the shared genetic background for a set of genetically correlated traits using SNP-level GWAS summary statistics. This framework called SHAHER is based on the construction of a linear combination of traits by maximizing the proportion of its...

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Detalles Bibliográficos
Autores principales: Svishcheva, Gulnara R., Tiys, Evgeny S., Elgaeva, Elizaveta E., Feoktistova, Sofia G., Timmers, Paul R. H. J., Sharapov, Sodbo Zh., Axenovich, Tatiana I., Tsepilov, Yakov A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602050/
https://www.ncbi.nlm.nih.gov/pubmed/36292579
http://dx.doi.org/10.3390/genes13101694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602050/
https://www.ncbi.nlm.nih.gov/pubmed/36292579
http://dx.doi.org/10.3390/genes13101694

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