Development of a Bicistronic Yellow Fever Live Attenuated Vaccine with Reduced Neurovirulence and Viscerotropism

The yellow fever (YF) live attenuated vaccine strain 17D (termed 17D) has been widely used for the prevention and control of YF disease. However, 17D retains significant neurovirulence and viscerotropism in mice, which is probably linked to the increased occurrences of serious adverse events followi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hong-Jiang, Guo, Yan, He, Meng-Jiao, Liu, Zhong-Yu, Ye, Qing, Huang, Xing-Yao, Deng, Yong-Qiang, Li, Xiao-Feng, Qin, Cheng-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602263/
https://www.ncbi.nlm.nih.gov/pubmed/35980184
http://dx.doi.org/10.1128/spectrum.02246-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602263/
https://www.ncbi.nlm.nih.gov/pubmed/35980184
http://dx.doi.org/10.1128/spectrum.02246-22

Ejemplares similares