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Noise-Reduction and Sensitivity-Enhancement of a Sleeping Beauty-Based Tet-On System

Tetracycline-inducible systems are widely used control elements for mammalian gene expression. Despite multiple iterations to improve inducibility, their use is still compromised by basal promoter activity in the absence of tetracyclines. In a mammalian system, we previously showed that the introduc...

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Detalles Bibliográficos
Autores principales: Saunderson, Sarah C., Hosseini-Rad, SM Ali, McLellan, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602432/
https://www.ncbi.nlm.nih.gov/pubmed/36292564
http://dx.doi.org/10.3390/genes13101679