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Capturing Structural Variants of Herpes Simplex Virus Genome in Full Length by Oxford Nanopore Sequencing

Genome sequencing and assembly of viral genomes within the Herpesviridae family, particularly herpes simplex virus (HSV), have been challenging due to the large size (~154 Kb), high GC content (68%), and nucleotide variations arising during replication. Oxford Nanopore Technology (ONT) has been succ...

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Detalles Bibliográficos
Autores principales: Saranathan, Rajagopalan, Asare, Emmanuel, Leung, Lawrence, de Oliveira, Anna Paula, Kaugars, Katherine E., Mulholland, Claire V., Lukose, Regy, Berney, Michael, Jacobs, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602439/
https://www.ncbi.nlm.nih.gov/pubmed/36040163
http://dx.doi.org/10.1128/spectrum.02285-22

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