A Novel Cryptic Clostridial Peptide That Kills Bacteria by a Cell Membrane Permeabilization Mechanism

This work reports detailed characteristics of the antimicrobial peptide Intestinalin (P30), which is derived from the LysC enzyme of Clostridium intestinale strain URNW. The peptide shows a broader antibacterial spectrum than the parental enzyme, showing potent antimicrobial activity against clinica...

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Detalles Bibliográficos
Autores principales: Szadkowska, Monika, Olewniczak, Michal, Kloska, Anna, Jankowska, Elzbieta, Kapusta, Malgorzata, Rybak, Bartosz, Wyrzykowski, Dariusz, Zmudzinska, Wioletta, Gieldon, Artur, Kocot, Aleksandra, Kaczorowska, Anna-Karina, Nierzwicki, Lukasz, Makowska, Joanna, Kaczorowski, Tadeusz, Plotka, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602519/
https://www.ncbi.nlm.nih.gov/pubmed/36094301
http://dx.doi.org/10.1128/spectrum.01657-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602519/
https://www.ncbi.nlm.nih.gov/pubmed/36094301
http://dx.doi.org/10.1128/spectrum.01657-22

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