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Effects of a Resistance Training Protocol on Physical Performance, Body Composition, Bone Metabolism, and Systemic Homeostasis in Patients Diagnosed with Parkinson’s Disease: A Pilot Study
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor impairments and it is correlated with loss of bone mineral density. This study aimed to analyze the effects of resistance training on bone metabolism, systemic homeostasis, body composition, and physical performance in p...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602560/ https://www.ncbi.nlm.nih.gov/pubmed/36293598 http://dx.doi.org/10.3390/ijerph192013022 |
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author | Amato, Alessandra Baldassano, Sara Vasto, Sonya Schirò, Giuseppe Davì, Chiara Drid, Patrik Dos Santos Mendes, Felipe Augusto Caldarella, Rosalia D’Amelio, Marco Proia, Patrizia |
author_facet | Amato, Alessandra Baldassano, Sara Vasto, Sonya Schirò, Giuseppe Davì, Chiara Drid, Patrik Dos Santos Mendes, Felipe Augusto Caldarella, Rosalia D’Amelio, Marco Proia, Patrizia |
author_sort | Amato, Alessandra |
collection | PubMed |
description | Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor impairments and it is correlated with loss of bone mineral density. This study aimed to analyze the effects of resistance training on bone metabolism, systemic homeostasis, body composition, and physical performance in people with PD. Thirteen subjects (age 64.83 ± 5.70) with PD diagnosis were recruited. Participants performed neuromuscular tests, body composition assessment, and blood sample analysis at baseline, and after an 11 weeks-training period. Each training session lasted 90 min, three times a week. The participants had significant improvements in the timed up and go (p < 0.01), sit to stand (p < 0.01), dominant peg-board (p < 0.05), dominant foot-reaction time (p < 0.01), and functional reach tests (p < 0.05). They showed better pressure foot distributions in the left forefoot (p < 0.05) and hindfoot (p < 0.05) and increased cervical right lateral bending angle (p < 0.05). The protocol affects bone metabolism markers osteocalcin (p < 0.05), calcium (p < 0.01), PTH (p < 0.01), the C-terminal telopeptide (CTX) (p < 0.01), and vitamin D (p < 0.05). Eleven weeks of resistance training improved manual dexterity, static and dynamic balance, reaction time, cervical ROM, and reduced bone loss in people with PD. |
format | Online Article Text |
id | pubmed-9602560 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96025602022-10-27 Effects of a Resistance Training Protocol on Physical Performance, Body Composition, Bone Metabolism, and Systemic Homeostasis in Patients Diagnosed with Parkinson’s Disease: A Pilot Study Amato, Alessandra Baldassano, Sara Vasto, Sonya Schirò, Giuseppe Davì, Chiara Drid, Patrik Dos Santos Mendes, Felipe Augusto Caldarella, Rosalia D’Amelio, Marco Proia, Patrizia Int J Environ Res Public Health Article Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor impairments and it is correlated with loss of bone mineral density. This study aimed to analyze the effects of resistance training on bone metabolism, systemic homeostasis, body composition, and physical performance in people with PD. Thirteen subjects (age 64.83 ± 5.70) with PD diagnosis were recruited. Participants performed neuromuscular tests, body composition assessment, and blood sample analysis at baseline, and after an 11 weeks-training period. Each training session lasted 90 min, three times a week. The participants had significant improvements in the timed up and go (p < 0.01), sit to stand (p < 0.01), dominant peg-board (p < 0.05), dominant foot-reaction time (p < 0.01), and functional reach tests (p < 0.05). They showed better pressure foot distributions in the left forefoot (p < 0.05) and hindfoot (p < 0.05) and increased cervical right lateral bending angle (p < 0.05). The protocol affects bone metabolism markers osteocalcin (p < 0.05), calcium (p < 0.01), PTH (p < 0.01), the C-terminal telopeptide (CTX) (p < 0.01), and vitamin D (p < 0.05). Eleven weeks of resistance training improved manual dexterity, static and dynamic balance, reaction time, cervical ROM, and reduced bone loss in people with PD. MDPI 2022-10-11 /pmc/articles/PMC9602560/ /pubmed/36293598 http://dx.doi.org/10.3390/ijerph192013022 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Amato, Alessandra Baldassano, Sara Vasto, Sonya Schirò, Giuseppe Davì, Chiara Drid, Patrik Dos Santos Mendes, Felipe Augusto Caldarella, Rosalia D’Amelio, Marco Proia, Patrizia Effects of a Resistance Training Protocol on Physical Performance, Body Composition, Bone Metabolism, and Systemic Homeostasis in Patients Diagnosed with Parkinson’s Disease: A Pilot Study |
title | Effects of a Resistance Training Protocol on Physical Performance, Body Composition, Bone Metabolism, and Systemic Homeostasis in Patients Diagnosed with Parkinson’s Disease: A Pilot Study |
title_full | Effects of a Resistance Training Protocol on Physical Performance, Body Composition, Bone Metabolism, and Systemic Homeostasis in Patients Diagnosed with Parkinson’s Disease: A Pilot Study |
title_fullStr | Effects of a Resistance Training Protocol on Physical Performance, Body Composition, Bone Metabolism, and Systemic Homeostasis in Patients Diagnosed with Parkinson’s Disease: A Pilot Study |
title_full_unstemmed | Effects of a Resistance Training Protocol on Physical Performance, Body Composition, Bone Metabolism, and Systemic Homeostasis in Patients Diagnosed with Parkinson’s Disease: A Pilot Study |
title_short | Effects of a Resistance Training Protocol on Physical Performance, Body Composition, Bone Metabolism, and Systemic Homeostasis in Patients Diagnosed with Parkinson’s Disease: A Pilot Study |
title_sort | effects of a resistance training protocol on physical performance, body composition, bone metabolism, and systemic homeostasis in patients diagnosed with parkinson’s disease: a pilot study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602560/ https://www.ncbi.nlm.nih.gov/pubmed/36293598 http://dx.doi.org/10.3390/ijerph192013022 |
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