Blockade of Wnt Secretion Attenuates Myocardial Ischemia–Reperfusion Injury by Modulating the Inflammatory Response

Wnt (a portmanteau of Wingless and Int-1) signaling in the adult heart is largely quiescent. However, there is accumulating evidence that it gets reactivated during the healing process after myocardial infarction (MI). We here tested the therapeutic potential of the Wnt secretion inhibitor LGK-974 o...

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Detalles Bibliográficos
Autores principales: Meyer, Ingmar Sören, Li, Xue, Meyer, Carina, Voloshanenko, Oksana, Pohl, Susann, Boutros, Michael, Katus, Hugo Albert, Frey, Norbert, Leuschner, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602582/
https://www.ncbi.nlm.nih.gov/pubmed/36293109
http://dx.doi.org/10.3390/ijms232012252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602582/
https://www.ncbi.nlm.nih.gov/pubmed/36293109
http://dx.doi.org/10.3390/ijms232012252

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