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Blockade of Wnt Secretion Attenuates Myocardial Ischemia–Reperfusion Injury by Modulating the Inflammatory Response
Wnt (a portmanteau of Wingless and Int-1) signaling in the adult heart is largely quiescent. However, there is accumulating evidence that it gets reactivated during the healing process after myocardial infarction (MI). We here tested the therapeutic potential of the Wnt secretion inhibitor LGK-974 o...
Autores principales: | Meyer, Ingmar Sören, Li, Xue, Meyer, Carina, Voloshanenko, Oksana, Pohl, Susann, Boutros, Michael, Katus, Hugo Albert, Frey, Norbert, Leuschner, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602582/ https://www.ncbi.nlm.nih.gov/pubmed/36293109 http://dx.doi.org/10.3390/ijms232012252 |
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