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Multi-Omics Analysis Reveals the Protection of Gasdermin D in Concanavalin A-Induced Autoimmune Hepatitis

Autoimmune hepatitis (AIH) is a progressive inflammation-associated liver injury. Pyroptosis is a novel inflammatory programmed cell death wherein gasdermin D (GSDMD) serves as the executioner. Our work challenged Gsdmd(−/−) mice with concanavalin A (ConA) to try to unveil the actual role of GSDMD i...

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Detalles Bibliográficos
Autores principales:	Wang, Kaicen, Wu, Wenrui, Jiang, Xianwan, Xia, Jiafeng, Lv, Longxian, Li, Shengjie, Zhuge, Aoxiang, Wu, Zhengjie, Wang, Qiangqiang, Wang, Shuting, Li, Lanjuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602755/ https://www.ncbi.nlm.nih.gov/pubmed/35972273 http://dx.doi.org/10.1128/spectrum.01717-22

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