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Thyrotropin-releasing hormone analog as a stable upper airway-preferring respiratory stimulant with arousal properties
Taltirelin is a stable, brain-penetrating thyrotropin-releasing hormone (TRH) analog with minimal endocrine activity and potential respiratory stimulant properties. Taltirelin’s receptor target shows high differential expression at the hypoglossal motor nucleus, and local taltirelin microperfusion i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602822/ https://www.ncbi.nlm.nih.gov/pubmed/36135952 http://dx.doi.org/10.1152/japplphysiol.00414.2022 |