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Thyrotropin-releasing hormone analog as a stable upper airway-preferring respiratory stimulant with arousal properties

Taltirelin is a stable, brain-penetrating thyrotropin-releasing hormone (TRH) analog with minimal endocrine activity and potential respiratory stimulant properties. Taltirelin’s receptor target shows high differential expression at the hypoglossal motor nucleus, and local taltirelin microperfusion i...

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Detalles Bibliográficos
Autores principales: Liu, Wen-Ying, Ladha, Raina, Liu, Hattie, Horner, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602822/
https://www.ncbi.nlm.nih.gov/pubmed/36135952
http://dx.doi.org/10.1152/japplphysiol.00414.2022