A pyrF-Based Efficient Genetic Manipulation Platform in Acinetobacter baumannii To Explore the Vital DNA Components of Adaptive Immunity for I-F CRISPR-Cas

Acinetobacter baumannii is an important pathogenic bacterium with multidrug resistance which causes infections with high mortality rates. In-depth genetic analysis of A. baumannii virulence and drug-resistant genes is highly desirable. In this study, we utilized the conserved pyrF-flanking fragment...

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Detalles Bibliográficos
Autores principales: Wu, Shuqi, Xu, Run, Su, Mengjiao, Gao, Can, Liu, Yang, Chen, Yujia, Luan, Guangxin, Jia, Xu, Wang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602844/
https://www.ncbi.nlm.nih.gov/pubmed/36047802
http://dx.doi.org/10.1128/spectrum.01957-22

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