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Molecular Determinants of Sulfadoxine-Pyrimethamine Resistance in Plasmodium falciparum Isolates from Central Africa between 2016 and 2021: Wide Geographic Spread of Highly Mutated Pfdhfr and Pfdhps Alleles

Sulfadoxine-pyrimethamine (SP) resistance impairs the efficacy of antimalarial drugs. Monitoring molecular markers in exported malaria infections provides an efficient way to trace the emergence of drug resistance in countries where malaria is endemic. Molecular markers in Pfdhfr and Pfdhps of 237 P...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaoxiao, Zhang, Xuan, Chen, Hualiang, Lu, Qiaoyi, Ruan, Wei, Chen, Zhiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602997/ https://www.ncbi.nlm.nih.gov/pubmed/36121226 http://dx.doi.org/10.1128/spectrum.02005-22

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