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Blockade of Platelet CysLT1R Receptor with Zafirlukast Counteracts Platelet Protumoral Action and Prevents Breast Cancer Metastasis to Bone and Lung

Metastases are the main cause of death in cancer patients, and platelets are largely known for their contribution in cancer progression. However, targeting platelets is highly challenging given their paramount function in hemostasis. Using a high-throughput screening and platelet-induced breast tumo...

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Detalles Bibliográficos
Autores principales:	Saier, Lou, Ribeiro, Johnny, Daunizeau, Thomas, Houssin, Audrey, Ichim, Gabriel, Barette, Caroline, Bouazza, Lamia, Peyruchaud, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603002/ https://www.ncbi.nlm.nih.gov/pubmed/36293074 http://dx.doi.org/10.3390/ijms232012221

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