Evaluation of Delafloxacin against a Burkholderia pseudomallei Efflux Mutant Panel

In vitro activities of delafloxacin and ciprofloxacin were evaluated against Burkholderia pseudomallei mutants expressing or lacking defined resistance-nodulation-cell division (RND) efflux pumps using CLSI methodology at pHs of 5.8 and 7.2. Delafloxacin MIC values were as much as 8-fold lower at pH...

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Detalles Bibliográficos
Autores principales: McCurdy, Sandra P., Somprasong, Nawarat, Schweizer, Herbert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603169/
https://www.ncbi.nlm.nih.gov/pubmed/35972245
http://dx.doi.org/10.1128/spectrum.00903-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603169/
https://www.ncbi.nlm.nih.gov/pubmed/35972245
http://dx.doi.org/10.1128/spectrum.00903-22

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