Cargando…

Evaluation of Delafloxacin against a Burkholderia pseudomallei Efflux Mutant Panel

In vitro activities of delafloxacin and ciprofloxacin were evaluated against Burkholderia pseudomallei mutants expressing or lacking defined resistance-nodulation-cell division (RND) efflux pumps using CLSI methodology at pHs of 5.8 and 7.2. Delafloxacin MIC values were as much as 8-fold lower at pH...

Descripción completa

Detalles Bibliográficos
Autores principales:	McCurdy, Sandra P., Somprasong, Nawarat, Schweizer, Herbert P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Observation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603169/ https://www.ncbi.nlm.nih.gov/pubmed/35972245 http://dx.doi.org/10.1128/spectrum.00903-22

Ejemplares similares

Efficacy of Delafloxacin against the Biothreat Pathogen Burkholderia pseudomallei
por: McCurdy, Sandra, et al.
Publicado: (2021)

Lipid A Remodeling Is a Pathoadaptive Mechanism That Impacts Lipopolysaccharide Recognition and Intracellular Survival of Burkholderia pseudomallei
por: Norris, Michael H., et al.
Publicado: (2018)

Exploring Cefiderocol Resistance Mechanisms in Burkholderia pseudomallei
por: Hall, Carina M., et al.
Publicado: (2023)

Burkholderia ubonensis Meropenem Resistance: Insights into Distinct Properties of Class A β-Lactamases in Burkholderia cepacia Complex and Burkholderia pseudomallei Complex Bacteria
por: Somprasong, Nawarat, et al.
Publicado: (2020)

Transcriptional and post-transcriptional regulation of PenA β-lactamase in acquired Burkholderia pseudomallei β-lactam resistance
por: Chirakul, Sunisa, et al.
Publicado: (2018)

Methods for genetic manipulation of Burkholderia gladioli pathovar cocovenenans
por: Somprasong, Nawarat, et al.
Publicado: (2010)

An in situ high-throughput screen identifies inhibitors of intracellular Burkholderia pseudomallei with therapeutic efficacy
por: Bulterys, Philip L., et al.
Publicado: (2019)

Antimicrobial Drug–Selection Markers for Burkholderia pseudomallei and B. mallei
por: Schweizer, Herbert P., et al.
Publicado: (2008)

The Burkholderia pseudomallei intracellular ‘TRANSITome’
por: Heacock-Kang, Yun, et al.
Publicado: (2021)

Efficacy of Delafloxacin versus Moxifloxacin against Bacterial Respiratory Pathogens in Adults with Community-Acquired Bacterial Pneumonia (CABP): Microbiology Results from the Delafloxacin Phase 3 CABP Trial
por: McCurdy, Sandra, et al.
Publicado: (2020)

Genome-scale analysis of the genes that contribute to Burkholderia pseudomallei biofilm formation identifies a crucial exopolysaccharide biosynthesis gene cluster
por: Borlee, Grace I., et al.
Publicado: (2017)

Structural diversity of Burkholderia pseudomallei lipopolysaccharides affects innate immune signaling
por: Norris, Michael H., et al.
Publicado: (2017)

Eﬄux pump-mediated drug resistance in Burkholderia
por: Podnecky, Nicole L., et al.
Publicado: (2015)

Development of Vaccines Against Burkholderia Pseudomallei
por: Patel, Natasha, et al.
Publicado: (2011)

Burkholderia pseudomallei Known Siderophores and Hemin Uptake Are Dispensable for Lethal Murine Melioidosis
por: Kvitko, Brian H., et al.
Publicado: (2012)

When it comes to drug discovery not all Gram‐negative bacterial biodefence pathogens are created equal: Burkholderia pseudomallei is different
por: Schweizer, Herbert P.
Publicado: (2012)

Polar Lipids of Burkholderia pseudomallei Induce Different Host Immune Responses
por: Gonzalez-Juarrero, Mercedes, et al.
Publicado: (2013)

Management of Accidental Laboratory Exposure to Burkholderia pseudomallei and B. mallei
por: Peacock, Sharon J., et al.
Publicado: (2008)

Molecular Investigations of PenA-mediated β-lactam Resistance in Burkholderia pseudomallei
por: Rholl, Drew A., et al.
Publicado: (2011)

2373. Evaluation of Delafloxacin Activity and Treatment Outcome for Phase 3 Acute Bacterial Skin and Skin Structure Infection Clinical Trial Anaerobic Isolates
por: Shortridge, Dee, et al.
Publicado: (2018)

Detection of glycoprotein of Burkholderia pseudomallei.
por: Khrapova, N P, et al.
Publicado: (1998)

Defense Mechanisms of Hepatocytes Against Burkholderia pseudomallei
por: Bast, Antje, et al.
Publicado: (2012)

Antibacterial activity of chitosan against Burkholderia pseudomallei
por: Kamjumphol, Watcharaporn, et al.
Publicado: (2017)

2230. Analysis of the Microbiological Data from the Delafloxacin (DLX) Phase 3 Community-acquired Bacterial Pneumonia (CABP) Trial
por: McCurdy, Sandra, et al.
Publicado: (2019)

Rapid Burkholderia pseudomallei identification and antibiotic resistance determination by bacteriophage amplification and MALDI-TOF MS
por: Cox, Christopher R, et al.
Publicado: (2014)

Autotransporters and Their Role in the Virulence of Burkholderia pseudomallei and Burkholderia mallei
por: Adler, Natalie R. Lazar, et al.
Publicado: (2011)

Activity of Delafloxacin When Tested Against Bacterial Surveillance Isolates Collected in the US and Europe During 2014–2016 as Part of a Global Surveillance Program
por: Flamm, Robert K, et al.
Publicado: (2017)

An Improved Selective Culture Medium Enhances the Isolation of Burkholderia pseudomallei from Contaminated Specimens
por: Goodyear, Andrew, et al.
Publicado: (2013)

Trimethoprim/sulfamethoxazole resistance in Burkholderia pseudomallei
por: Dance, D.A.B., et al.
Publicado: (2014)

Burkholderia collagen-like protein 8, Bucl8, is a unique outer membrane component of a putative tetrapartite efflux pump in Burkholderia pseudomallei and Burkholderia mallei
por: Grund, Megan E., et al.
Publicado: (2020)

Mechanisms of Resistance to Folate Pathway Inhibitors in Burkholderia pseudomallei: Deviation from the Norm
por: Podnecky, Nicole L., et al.
Publicado: (2017)

Survival of Burkholderia pseudomallei in Water
por: Moore, Richard A, et al.
Publicado: (2008)

Misidentification of Burkholderia pseudomallei, China
por: Wu, Bin, et al.
Publicado: (2021)

Pathogenicity and virulence of Burkholderia pseudomallei
por: Bzdyl, Nicole M., et al.
Publicado: (2022)

Persistent Gastric Colonization with Burkholderia pseudomallei and Dissemination from the Gastrointestinal Tract following Mucosal Inoculation of Mice
por: Goodyear, Andrew, et al.
Publicado: (2012)

Burkholderia pseudomallei Antibodies in Children, Cambodia
por: Wuthiekanun, Vanaporn, et al.
Publicado: (2008)

Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis)
por: Birnie, Emma, et al.
Publicado: (2019)

Seroepidemiology of Burkholderia pseudomallei, Etiologic Agent of Melioidosis, in the Ouest and Sud-Est Departments of Haiti
por: Weppelmann, Thomas A., et al.
Publicado: (2018)

Distribution of Serological Response to Burkholderia pseudomallei in Swine from Three Provinces of Vietnam
por: Norris, Michael H., et al.
Publicado: (2020)

A Burkholderia pseudomallei Colony Variant Necessary for Gastric Colonization
por: Austin, C. R., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_05ckajrtng2auecqlsviss20l9