Host Cell Neddylation Facilitates Alphaherpesvirus Entry in a Virus-Specific and Cell-Dependent Manner

Herpes simplex virus 1 (HSV-1) commandeers the host cell proteasome at several steps of its replication cycle, including entry. Here we demonstrate that HSV-2, pseudorabies virus (PRV), and bovine herpesvirus 1 (BoHV-1) entry are blocked by bortezomib, a proteasome inhibitor that is an FDA-approved...

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Detalles Bibliográficos
Autores principales: Lee, Becky H., Tebaldi, Giulia, Pritchard, Suzanne M., Nicola, Anthony V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603186/
https://www.ncbi.nlm.nih.gov/pubmed/36173301
http://dx.doi.org/10.1128/spectrum.03114-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603186/
https://www.ncbi.nlm.nih.gov/pubmed/36173301
http://dx.doi.org/10.1128/spectrum.03114-22

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