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Leishmania major Strain-Dependent Macrophage Activation Contributes to Pathogenicity in the Absence of Lymphocytes

Infection of C57BL/6 wild-type mice with Leishmania major 5-ASKH or Friedlin strains results in relatively similar pathogenicity with self-healing lesions within weeks. Parasite clearance depends on nitric oxide production by activated macrophages in response to cytokines produced mainly by CD4(+) T...

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Detalles Bibliográficos
Autores principales:	Alshaweesh, Jalal, Nakamura, Risa, Tanaka, Yuka, Hayashishita, Mizuki, Musa, Abu, Kikuchi, Mihoko, Inaoka, Daniel Ken, Hamano, Shinjiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603372/ https://www.ncbi.nlm.nih.gov/pubmed/36190414 http://dx.doi.org/10.1128/spectrum.01126-22

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