Boron Clusters as Enhancers of RNase H Activity in the Smart Strategy of Gene Silencing by Antisense Oligonucleotides

Boron cluster-conjugated antisense oligonucleotides (B-ASOs) have already been developed as therapeutic agents with “two faces”, namely as potential antisense inhibitors of gene expression and as boron carriers for boron neutron capture therapy (BNCT). The previously observed high antisense activity...

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Detalles Bibliográficos
Autores principales: Kaniowski, Damian, Kulik, Katarzyna, Suwara, Justyna, Ebenryter-Olbińska, Katarzyna, Nawrot, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603397/
https://www.ncbi.nlm.nih.gov/pubmed/36293047
http://dx.doi.org/10.3390/ijms232012190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603397/
https://www.ncbi.nlm.nih.gov/pubmed/36293047
http://dx.doi.org/10.3390/ijms232012190

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