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Boron Clusters as Enhancers of RNase H Activity in the Smart Strategy of Gene Silencing by Antisense Oligonucleotides
Boron cluster-conjugated antisense oligonucleotides (B-ASOs) have already been developed as therapeutic agents with “two faces”, namely as potential antisense inhibitors of gene expression and as boron carriers for boron neutron capture therapy (BNCT). The previously observed high antisense activity...
Autores principales: | Kaniowski, Damian, Kulik, Katarzyna, Suwara, Justyna, Ebenryter-Olbińska, Katarzyna, Nawrot, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603397/ https://www.ncbi.nlm.nih.gov/pubmed/36293047 http://dx.doi.org/10.3390/ijms232012190 |
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