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NLRP1 in Cutaneous SCCs: An Example of the Complex Roles of Inflammasomes in Cancer Development

Protein complexes termed inflammasomes ensure tissue protection from pathogenic and sterile stressors by induction of inflammation. This is mediated by different caspase-1-induced downstream pathways, including activation of the pro-inflammatory cytokines proIL-1β and -18, induction of a lytic type...

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Detalles Bibliográficos
Autores principales: Di Filippo, Michela, Hennig, Paulina, Karakaya, Tugay, Slaufova, Marta, Beer, Hans-Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603439/
https://www.ncbi.nlm.nih.gov/pubmed/36293159
http://dx.doi.org/10.3390/ijms232012308

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