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Engineered Human Intervertebral Disc Model Inducing Degenerative Microglial Proinflammation
Degeneration of the intervertebral disc (IVD) is a major contributor to low back pain (LBP). IVD degeneration is characterized by abnormal production of inflammatory cytokines secreted by IVD cells. Although the underlying molecular mechanisms of LBP have not been elucidated, increasing evidence sug...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603448/ https://www.ncbi.nlm.nih.gov/pubmed/36293070 http://dx.doi.org/10.3390/ijms232012216 |