Next Steps in Prader-Willi Syndrome Research: On the Relationship between Genotype and Phenotype

This article reviews what we know of the phenotype and genotype of Prader-Willi syndrome and hypothesizes two possible paths from phenotype to genotype. It then suggests research that may strengthen the case for one or other of these hypotheses.

Detalles Bibliográficos
Autores principales: Whittington, Joyce, Holland, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603642/
https://www.ncbi.nlm.nih.gov/pubmed/36292940
http://dx.doi.org/10.3390/ijms232012089
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author Whittington, Joyce
Holland, Anthony
author_facet Whittington, Joyce
Holland, Anthony
author_sort Whittington, Joyce
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description This article reviews what we know of the phenotype and genotype of Prader-Willi syndrome and hypothesizes two possible paths from phenotype to genotype. It then suggests research that may strengthen the case for one or other of these hypotheses.
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spelling pubmed-96036422022-10-27 Next Steps in Prader-Willi Syndrome Research: On the Relationship between Genotype and Phenotype Whittington, Joyce Holland, Anthony Int J Mol Sci Hypothesis This article reviews what we know of the phenotype and genotype of Prader-Willi syndrome and hypothesizes two possible paths from phenotype to genotype. It then suggests research that may strengthen the case for one or other of these hypotheses. MDPI 2022-10-11 /pmc/articles/PMC9603642/ /pubmed/36292940 http://dx.doi.org/10.3390/ijms232012089 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Hypothesis
Whittington, Joyce
Holland, Anthony
Next Steps in Prader-Willi Syndrome Research: On the Relationship between Genotype and Phenotype
title Next Steps in Prader-Willi Syndrome Research: On the Relationship between Genotype and Phenotype
title_full Next Steps in Prader-Willi Syndrome Research: On the Relationship between Genotype and Phenotype
title_fullStr Next Steps in Prader-Willi Syndrome Research: On the Relationship between Genotype and Phenotype
title_full_unstemmed Next Steps in Prader-Willi Syndrome Research: On the Relationship between Genotype and Phenotype
title_short Next Steps in Prader-Willi Syndrome Research: On the Relationship between Genotype and Phenotype
title_sort next steps in prader-willi syndrome research: on the relationship between genotype and phenotype
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603642/
https://www.ncbi.nlm.nih.gov/pubmed/36292940
http://dx.doi.org/10.3390/ijms232012089
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