Cargando…

SENP2 Promotes VSMC Phenotypic Switching via Myocardin De-SUMOylation

Myocardin is a master regulator of smooth muscle cell (SMC) differentiation, which induces the expression of smooth-muscle-specific genes through its direct association with serum response factor (SRF). During the past two decades, significant insights have been obtained regarding the regulatory con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Min, Cai, Zhaohua, Jiang, Yangjing, Huo, Huanhuan, Shen, Linghong, He, Ben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603890/ https://www.ncbi.nlm.nih.gov/pubmed/36293488 http://dx.doi.org/10.3390/ijms232012637

Ejemplares similares

Redox-sensitive enzyme SENP3 mediates vascular remodeling via de-SUMOylation of β-catenin and regulation of its stability
por: Cai, Zhaohua, et al.
Publicado: (2021)

SENP1 and SENP2 regulate SUMOylation of amyloid precursor protein
por: Maruyama, Takuma, et al.
Publicado: (2018)

SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis
por: Cubeñas-Potts, Caelin, et al.
Publicado: (2013)

Angiotensin II Promotes White Adipose Tissue Browning and Lipolysis in Mice
por: Cai, Zhaohua, et al.
Publicado: (2022)

SENP5 deteriorates traumatic brain injury via SUMO2-dependent suppression of E2F1 SUMOylation: SENP5 promotes TBI via inhibiting E2F1 SUMOylation
por: Ding, Yanfu, et al.
Publicado: (2023)

SENP1 participates in the dynamic regulation of Elk-1 SUMOylation
por: Witty, James, et al.
Publicado: (2010)

SENP5 mediates breast cancer invasion via a TGFβRI SUMOylation cascade
por: Cashman, Rivki, et al.
Publicado: (2014)

Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2
por: Wang, Ronghua, et al.
Publicado: (2017)

SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
por: Yu, Xiaoyan, et al.
Publicado: (2018)

SMYD2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Intimal Hyperplasia via Interaction with Myocardin
por: Zhou, Yu, et al.
Publicado: (2023)

SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1
por: Wang, Ju-Qiong, et al.
Publicado: (2020)

SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
por: Cui, Chun-Ping, et al.
Publicado: (2017)

De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells
por: Ren, Yan-hua, et al.
Publicado: (2014)

SENP3-mediated deSUMOylation of Drp1 facilitates interaction with Mff to promote cell death
por: Guo, Chun, et al.
Publicado: (2017)

SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis
por: Yu, Luyang, et al.
Publicado: (2010)

SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer
por: Zhou, Z, et al.
Publicado: (2016)

Regulation of Serotonin 1A Receptor SUMOylation by SENP2 and PIASxα
por: Gupta, Sugandha, et al.
Publicado: (2021)

Mitochondria spatially and temporally modulate VSMC phenotypes via interacting with cytoskeleton in cardiovascular diseases
por: Li, Jingwen, et al.
Publicado: (2023)

SENP1 Is a Crucial Regulator for Cell Senescence through DeSUMOylation of Bmi1
por: Xia, Nansong, et al.
Publicado: (2016)

SENP1 is a crucial promotor for hepatocellular carcinoma through deSUMOylation of UBE2T
por: Tao, Yifeng, et al.
Publicado: (2020)

Knockdown of SENP1 inhibits HIF-1α SUMOylation and suppresses oncogenic CCNE1 in Wilms tumor
por: Zhu, Shibo, et al.
Publicado: (2021)

SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia
por: Guo, Chun, et al.
Publicado: (2013)

The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis
por: Qiu, Cong, et al.
Publicado: (2017)

Enhanced SUMOylation and SENP-1 protein levels following oxygen and glucose deprivation in neurones
por: Cimarosti, Helena, et al.
Publicado: (2012)

Protective role of the deSUMOylating enzyme SENP3 in myocardial ischemia-reperfusion injury
por: Rawlings, Nadiia, et al.
Publicado: (2019)

AKT Mediates Adiponectin-Dependent Regulation of VSMC Phenotype
por: Cullen, Abigail E., et al.
Publicado: (2023)

SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation
por: Liu, Tingting, et al.
Publicado: (2023)

The protease SENP2 controls hepatic gluconeogenesis by regulating the SUMOylation of the fuel sensor AMPKα
por: Dou, Xin, et al.
Publicado: (2021)

Myocardin in biology and disease
por: Miano, Joseph M
Publicado: (2015)

In Search of Novel Targets for Heart Disease: Myocardin and Myocardin-Related Transcriptional Cofactors
por: Mikhailov, Alexander T., et al.
Publicado: (2012)

SENP1 promotes triple-negative breast cancer invasion and metastasis via enhancing CSN5 transcription mediated by GATA1 deSUMOylation
por: Gao, Yongchang, et al.
Publicado: (2022)

SENP3 affects the expression of PYCR1 to promote bladder cancer proliferation and EMT transformation by deSUMOylation of STAT3
por: Li, Zhuo, et al.
Publicado: (2022)

MicroRNA-134-5p Regulates Media Degeneration through Inhibiting VSMC Phenotypic Switch and Migration in Thoracic Aortic Dissection
por: Wang, Ying, et al.
Publicado: (2019)

SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis
por: He, Qi, et al.
Publicado: (2023)

SENP6 regulates localization and nuclear condensation of DNA damage response proteins by group deSUMOylation
por: Claessens, Laura A., et al.
Publicado: (2023)

Leptin accelerates BMSC transformation into vertebral epiphyseal plate chondrocytes by activating SENP1‐mediated deSUMOylation of SIRT3
por: Li, Xiaomiao, et al.
Publicado: (2023)

SENP1-mediated NEMO deSUMOylation in adipocytes limits inflammatory responses and type-1 diabetes progression
por: Shao, Lan, et al.
Publicado: (2015)

SENP1-mediated deSUMOylation of JAK2 regulates its kinase activity and platinum drug resistance
por: Li, Jing, et al.
Publicado: (2021)

SENP3‐mediated TIP60 deSUMOylation is required for DNA‐PKcs activity and DNA damage repair
por: Han, Yang, et al.
Publicado: (2022)

SRF SUMOylation modulates smooth muscle phenotypic switch and vascular remodeling
por: Xu, Yue, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e0l5qmhf52mjjfq74qjmae7da8