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Structural and functional analysis of SNP rs76740365 G>A in exon-3 of the alpha A-crystallin gene in lens epithelial cells

PURPOSE: To clarify the effect of a previously identified single nucleotide polymorphism (SNP; rs76740365 G>A) in the exon-3 of the alpha A-crystallin (CRYAA) gene on the properties of CRYAA and to investigate its function in human lens epithelial cells (HLECs). METHODS: The human recombinant wil...

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Detalles Bibliográficos
Autores principales:	Zhao, Zhennan, Sun, Yang, Fan, Qi, Jiang, Yongxiang, Lu, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603911/ https://www.ncbi.nlm.nih.gov/pubmed/36338667

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