Discovery of Mitophagy Inhibitors with Therapeutic Potential in Different Familial Amyotrophic Lateral Sclerosis Mutations

Mitophagy is the selective degradation of mitochondria by autophagy. It promotes the turnover of mitochondria and prevents the accumulation of dysfunctional mitochondria, which can lead to cellular degeneration. Mitophagy is known to be altered in several pathological conditions, especially in neuro...

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Detalles Bibliográficos
Autores principales: Maestro, Ines, de la Ballina, Laura R., Porras, Gracia, Corrochano, Silvia, De Lago, Eva, Simonsen, Anne, Boya, Patricia, Martinez, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603920/
https://www.ncbi.nlm.nih.gov/pubmed/36293534
http://dx.doi.org/10.3390/ijms232012676

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