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Blood Reflux-Induced Epigenetic Factors HDACs and DNMTs Are Associated with the Development of Human Chronic Venous Disease

Blood reflux and metabolic regulation play important roles in chronic venous disease (CVD) development. Histone deacetylases (HDACs) and DNA methyltransferases (DNMTs) serve as repressors that inhibit metabolic signaling, which is induced by proatherogenic flow to promote aortic endothelial cell (EC...

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Detalles Bibliográficos
Autores principales: Chang, Shun-Fu, Tsai, Hsiao-En, Kuo, Jong-Tar, Ruan, Yu-Rong, Chen, Chiu-Yen, Wang, Shin-Yi, Liu, Po-Yu, Lee, Ding-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603923/
https://www.ncbi.nlm.nih.gov/pubmed/36293392
http://dx.doi.org/10.3390/ijms232012536