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Blood Reflux-Induced Epigenetic Factors HDACs and DNMTs Are Associated with the Development of Human Chronic Venous Disease
Blood reflux and metabolic regulation play important roles in chronic venous disease (CVD) development. Histone deacetylases (HDACs) and DNA methyltransferases (DNMTs) serve as repressors that inhibit metabolic signaling, which is induced by proatherogenic flow to promote aortic endothelial cell (EC...
Autores principales: | Chang, Shun-Fu, Tsai, Hsiao-En, Kuo, Jong-Tar, Ruan, Yu-Rong, Chen, Chiu-Yen, Wang, Shin-Yi, Liu, Po-Yu, Lee, Ding-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603923/ https://www.ncbi.nlm.nih.gov/pubmed/36293392 http://dx.doi.org/10.3390/ijms232012536 |
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