Intact Type I Interferon Receptor Signaling Prevents Hepatocellular Necrosis but Not Encephalitis in a Dose-Dependent Manner in Rift Valley Fever Virus Infected Mice

Rift Valley fever (RVF) is a zoonotic and emerging disease, caused by the RVF virus (RVFV). In ruminants, it leads to “abortion storms” and enhanced mortality rates in young animals, whereas in humans it can cause symptoms like severe hemorrhagic fever or encephalitis. The role of the innate and ada...

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Detalles Bibliográficos
Autores principales: Michaely, Lukas Mathias, Schuwerk, Lukas, Allnoch, Lisa, Schön, Kathleen, Waltl, Inken, Larsen, Pia-Katharina, Pavlou, Andreas, Prajeeth, Chittappen Kandiyil, Rimmelzwaan, Guus F., Becker, Stefanie C., Kalinke, Ulrich, Baumgärtner, Wolfgang, Gerhauser, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603964/
https://www.ncbi.nlm.nih.gov/pubmed/36293352
http://dx.doi.org/10.3390/ijms232012492

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