Cargando…

Identifying Hub Genes Associated with Neoadjuvant Chemotherapy Resistance in Breast Cancer and Potential Drug Repurposing for the Development of Precision Medicine

Breast cancer is the second leading cause of morbidity and mortality in women worldwide. Despite advancements in the clinical application of neoadjuvant chemotherapy (NAC), drug resistance remains a major concern hindering treatment efficacy. Thus, identifying the key genes involved in driving NAC r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saha Detroja, Trishna, Detroja, Rajesh, Mukherjee, Sumit, Samson, Abraham O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603969/ https://www.ncbi.nlm.nih.gov/pubmed/36293493 http://dx.doi.org/10.3390/ijms232012628

Ejemplares similares

Text-Mining Approach to Identify Hub Genes of Cancer Metastasis and Potential Drug Repurposing to Target Them
por: Detroja, Trishna Saha, et al.
Publicado: (2022)

Virtual Screening for FDA-Approved Drugs That Selectively Inhibit Arginase Type 1 and 2
por: Detroja, Trishna Saha, et al.
Publicado: (2022)

The Landscape of Novel Expressed Chimeric RNAs in Rheumatoid Arthritis
por: Detroja, Rajesh, et al.
Publicado: (2022)

The Landscape of Expressed Chimeric Transcripts in the Blood of Severe COVID-19 Infected Patients
por: Mukherjee, Sunanda Biswas, et al.
Publicado: (2023)

Immunoinformatics and Structural Analysis for Identification of Immunodominant Epitopes in SARS-CoV-2 as Potential Vaccine Targets
por: Mukherjee, Sumit, et al.
Publicado: (2020)

COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics
por: Tworowski, Dmitry, et al.
Publicado: (2020)

Autoimmune Disease Classification Based on PubMed Text Mining
por: Samuels, Hadas, et al.
Publicado: (2022)

Draft Genome Sequence of the Yeast Saccharomyces cerevisiae GUJ105 From Gujarat, India
por: Badapanda, Chandan, et al.
Publicado: (2016)

ChiTaH: a fast and accurate tool for identifying known human chimeric sequences from high-throughput sequencing data
por: Detroja, Rajesh, et al.
Publicado: (2021)

Computational analysis of sense-antisense chimeric transcripts reveals their potential regulatory features and the landscape of expression in human cells
por: Mukherjee, Sumit, et al.
Publicado: (2021)

Clinico-Investigative Profile of Hereditary Spastic Paraplegia in Children
por: Kamate, Mahesh, et al.
Publicado: (2019)

Isolated and Asymmetric Basal Ganglia Involvement in Early Subacute Sclerosing Panencephalitis
por: Kamate, Mahesh, et al.
Publicado: (2019)

Proteomics and Drug Repurposing in CLL towards Precision Medicine
por: Mavridou, Dimitra, et al.
Publicado: (2021)

Incipient Sympatric Speciation and Evolution of Soil Bacteria Revealed by Metagenomic and Structured Non-Coding RNAs Analysis
por: Mukherjee, Sumit, et al.
Publicado: (2022)

Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs
por: Niculescu, A. B., et al.
Publicado: (2019)

Repurposing drugs to treat cardiovascular disease in the era of precision medicine
por: Abdelsayed, Mena, et al.
Publicado: (2022)

Enhanced Antihypertensive Activity of Candesartan Cilexetil Nanosuspension: Formulation, Characterization and Pharmacodynamic Study
por: Detroja, Chetan, et al.
Publicado: (2011)

The chromatin remodeler Chd1 regulates cohesin in budding yeast and humans
por: Boginya, Alexandra, et al.
Publicado: (2019)

KCNQ2 Encephalopathy and Effect of Early Treatment on the Clinical Phenotype
por: Kamate, Mahesh, et al.
Publicado: (2022)

Neuronal Ceroid Lipofuscinoses in Children
por: Kamate, Mahesh, et al.
Publicado: (2021)

ChiTaRS 5.0: the comprehensive database of chimeric transcripts matched with druggable fusions and 3D chromatin maps
por: Balamurali, Deepak, et al.
Publicado: (2020)

Predictive Biomarkers of Response to Neoadjuvant Chemotherapy in Breast Cancer: Current and Future Perspectives for Precision Medicine
por: Derouane, Françoise, et al.
Publicado: (2022)

Clinical and Molecular Characterization of a Rare Case of BNT162b2 mRNA COVID-19 Vaccine-Associated Myositis
por: Magen, Eli, et al.
Publicado: (2022)

Precision medicine for mood disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs
por: Le-Niculescu, H., et al.
Publicado: (2021)

Network Medicine Framework for Identifying Drug Repurposing Opportunities for COVID-19
por: Morselli Gysi, Deisy, et al.
Publicado: (2020)

Network medicine framework for identifying drug-repurposing opportunities for COVID-19
por: Morselli Gysi, Deisy, et al.
Publicado: (2021)

“Hard” Drug Repurposing for Precision Oncology: The Missing Link?
por: Pantziarka, Pan, et al.
Publicado: (2018)

Towards precision medicine for anxiety disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs
por: Roseberry, K., et al.
Publicado: (2023)

Invasion and Metastasis as a Central Hallmark of Breast Cancer
por: Saha, Trishna, et al.
Publicado: (2021)

High-Throughput Screening of the Repurposing Hub Library to Identify Drugs with Novel Inhibitory Activity against Candida albicans and Candida auris Biofilms
por: Ajetunmobi, Olabayo H., et al.
Publicado: (2023)

Meta-Data Analysis to Explore the Hub of the Hub-Genes That Influence SARS-CoV-2 Infections Highlighting Their Pathogenetic Processes and Drugs Repurposing
por: Mosharaf, Md. Parvez, et al.
Publicado: (2022)

Challenges for Effective Glycemic control in T2DM during Covid-19 pandemic and Use of Glimepiride/Metformin FDC: Opinion from Indian Clinicians
por: Gandhi, Alka, et al.
Publicado: (2022)

Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer
por: Emanuelli, Andrea, et al.
Publicado: (2019)

Drug repurposing for breast cancer therapy: Old weapon for new battle
por: Aggarwal, Sadhna, et al.
Publicado: (2021)

Transcriptomics-Based Drug Repurposing Approach Identifies Novel Drugs against Sorafenib-Resistant Hepatocellular Carcinoma
por: Regan-Fendt, Kelly, et al.
Publicado: (2020)

Transcriptomics-based network medicine approach identifies metformin as a repurposable drug for atrial fibrillation
por: Lal, Jessica C., et al.
Publicado: (2022)

Drug Repurposing Screening Identifies Tioconazole as an ATG4 Inhibitor that Suppresses Autophagy and Sensitizes Cancer Cells to Chemotherapy
por: Liu, Pei-Feng, et al.
Publicado: (2018)

Cardiotoxicity and Chemotherapy—The Role of Precision Medicine
por: Viswanathan, Thyla, et al.
Publicado: (2021)

A network medicine approach for identifying diagnostic and prognostic biomarkers and exploring drug repurposing in human cancer
por: Zhang, Le, et al.
Publicado: (2022)

Systematic Repurposing Screening in Xenograft Models Identifies Approved Drugs with Novel Anti-Cancer Activity
por: Roix, Jeffrey J., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_n7b6lsc140rkj4cre4oac6lp2f