Serial Passaging of Seasonal H3N2 Influenza A/Singapore/G2-31.1/2014 Virus in MDCK-SIAT1 Cells and Primary Chick Embryo Cells Generates HA D457G Mutation and Other Variants in HA, NA, PB1, PB1-F2, and NS1

Influenza remains one of the most prevalent viruses circulating amongst humans and has resulted in several pandemics. The prevention and control of H3N2 influenza is complicated by its propensity for evolution, which leads to vaccine mismatch and reduced vaccine efficacies. This study employed the s...

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Detalles Bibliográficos
Autores principales: Aw, Daryl Zheng Hao, Heng, Keng Kai, Heok, Jovian Yee Han, Kong, Xin Yang, Chen, Hui, Zhang, Tong, Zhai, Weiwei, Chow, Vincent T. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604028/
https://www.ncbi.nlm.nih.gov/pubmed/36293269
http://dx.doi.org/10.3390/ijms232012408

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